No association between the Clara cell secretory protein (CC16) gene polymorphism and personality traits

被引：0
作者：
Tochigi, Mamoru
Otowa, Takeshi
Hibino, Hiroyuki
Kato, Chieko
Marui, Tetsuya
Ohtani, Toshiyuki
Umekage, Tadashi
Kato, Nobumasa
Sasaki, Tsukasa
机构：
[1] Univ Tokyo, Grad Sch Med, Dept Neuropsychiat, Bunkyo Ku, Tokyo 1138655, Japan
[2] Univ Tokyo, Hlth Serv Ctr, Bunkyo Ku, Tokyo 1138655, Japan
来源：
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | 2006年 / 30卷 / 06期
关键词：
Clara cell secretory protein (CC16); personality traits; the Revised NEO Personality Inventory (NEO PI-R); the State-Trait Anxiety Inventory (STAI);
D O I：
10.1016/j.pnpbp.2006.04.019
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Clara cell secretory protein (CC16) is an anti-inflammatory protein expressed in the respiratory tract. Several studies have suggested the association between CC16 and mental disturbances, such as schizophrenia, depression, and post-traumatic stress disorder. In the present study, we investigated the association between the CC16 gene A38G polymorphism and personality traits in 214 healthy Japanese subjects. Personality traits were evaluated by using the Revised NEO Personality Inventory (NEO PI-R) and the State-Trait Anxiety Inventory (STAI). As a result, no significant association was observed between the genotypes and the scores of the NEO PI-R. or the STAI. The present results suggest that CC16 may not have a major role in the development of personality traits. (c) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码：1122 / 1124
页数：3
相关论文
共 17 条
  • [1] Season of birth and inflammatory response system in schizophrenia
    Altamura, AC
    Bassetti, R
    Bocchio, L
    Santini, A
    Mundo, E
    [J]. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2003, 27 (05) : 879 - 880
  • [2] [Anonymous], STAI MANUAL
  • [3] Association between asthma-related phenotypes and the CC16 A38G polymorphism in an unselected population of young adult Danes
    Candelaria, PV
    Backer, V
    Laing, IA
    Porsbjerg, C
    Nepper-Christensen, S
    de Klerk, N
    Goldblatt, J
    Le Souëf, PN
    [J]. IMMUNOGENETICS, 2005, 57 (1-2) : 25 - 32
  • [4] Costa P. T., 1992, PSYCHOL ASSESSMENT R
  • [5] POTENT INHIBITION OF BOTH HUMAN INTERFERON-GAMMA PRODUCTION AND BIOLOGIC ACTIVITY BY THE CLARA CELL PROTEIN CC16
    DIERYNCK, I
    BERNARD, A
    ROELS, H
    DELEY, M
    [J]. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 1995, 12 (02) : 205 - 210
  • [6] Pneumoproteinaemia: a new perspective in the assessment of lung disorders
    Hermans, C
    Bernard, A
    [J]. EUROPEAN RESPIRATORY JOURNAL, 1998, 11 (04) : 801 - 803
  • [7] Clara cell secretory protein (CC16) gene polymorphism and schizophrenia in humans
    Hori, H
    Ohmori, O
    Shinkai, T
    Kojima, H
    Nakamura, J
    [J]. NEUROSCIENCE LETTERS, 2001, 298 (01) : 75 - 77
  • [8] A polymorphism of the CC16 gene is associated with an increased risk of asthma
    Laing, IA
    Goldblatt, J
    Eber, E
    Hayden, CM
    Rye, PJ
    Gibson, NA
    Palmer, LJ
    Burton, PR
    Le Souëf, PN
    [J]. JOURNAL OF MEDICAL GENETICS, 1998, 35 (06) : 463 - 467
  • [9] Association between plasma CC16 levels, the A38G polymorphism, and asthma
    Laing, IA
    Hermans, C
    Bernard, A
    Burton, PR
    Goldblatt, J
    Le Souëf, PN
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2000, 161 (01) : 124 - 127
  • [10] The inflammatory response system in treatment-resistant schizophrenia:: increased serum interleukin-6
    Lin, A
    Kenis, G
    Bignotti, S
    Tura, GJB
    De Jong, R
    Bosmans, E
    Pioli, R
    Altamura, C
    Scharpé, S
    Maes, M
    [J]. SCHIZOPHRENIA RESEARCH, 1998, 32 (01) : 9 - 15
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