Immunomodulatory sesquiterpene glycosides from Dendrobium nobile

被引:99
作者
Ye, QH [1 ]
Qin, GW [1 ]
Zhao, WM [1 ]
机构
[1] Chinese Acad Sci, Shanghai Inst biol Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China
关键词
Dendrobium nobile; Orchidaceae; sesquiterpene glycosides; dendrosides D; E; F; and G; immunomodulatory activity;
D O I
10.1016/S0031-9422(02)00484-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Four sesquiterpene glycosides with alloaromadendrane, emmotin, and picrotoxane type aglycones were isolated from the stems of Dendrobium nobile Lindl (Orchidaceae). Their structures were determined by spectroscopic methods and chemical reactions. Immunomodulatory activity of the isolates was evaluated in vitro. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:885 / 890
页数:6
相关论文
共 20 条
[1]  
Chen KK, 1935, J BIOL CHEM, V111, P653
[2]  
HARA S, 1987, CHEM PHARM BULL, V35, P501
[3]   STUDIES ON ORCHIDACEAE ALKALOIDS .27. QUATERNARY-SALTS OF DENDROBINE TYPE FROM DENDROBIUM-NOBILE LINDL [J].
HEDMAN, K ;
LEANDER, K .
ACTA CHEMICA SCANDINAVICA, 1972, 26 (08) :3177-3180
[4]  
*JINGS NEW MED COL, 1986, DICT CHIN HERB MED, P586
[5]   IN-VITRO AND IN-VIVO ANTITUMORAL PHENANTHRENES FROM THE AERIAL PARTS OF DENDROBIUM NOBILE [J].
LEE, YH ;
PARK, JD ;
BAEK, NI ;
KIM, SI ;
AHN, BZ .
PLANTA MEDICA, 1995, 61 (02) :178-180
[6]  
LI MF, 1991, CHINESE J ORG CHEM, V11, P219
[7]  
LI XY, 1990, ACTA PHARM SINIC, V11, P542
[8]  
LIMA DPD, 1999, J CHEM RES S, P396
[9]   Antimutagenic activity of gigantol from Dendrobium nobile [J].
Miyazawa, M ;
Shimamura, H ;
Nakamura, S ;
Kameoka, H .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1997, 45 (08) :2849-2853
[10]   New picrotoxinin-type and dendrobine-type sesquiterpenoids from Dendrobium Snowflake 'Red Star' [J].
Morita, H ;
Fujiwara, M ;
Yoshida, N ;
Kobayashi, J .
TETRAHEDRON, 2000, 56 (32) :5801-5805