B regulatory cells in allergy

被引:30
|
作者
Ma, Siyuan [1 ,2 ]
Satitsuksanoa, Pattraporn [1 ]
Jansen, Kirstin [1 ]
Cevhertas, Lacin [1 ,3 ]
van de Veen, Willem [1 ]
Akdis, Mubeccel [1 ]
机构
[1] Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland
[2] Capital Med Univ, Beijing TongRen Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
[3] Bursa Uludag Univ, Inst Hlth Sci, Dept Med Immunol, Bursa, Turkey
基金
瑞士国家科学基金会;
关键词
allergen immunotherapy; Breg cells; IL‐ 10; tolerance; MODIFIED TH2 RESPONSE; B10; CELLS; T-CELLS; IMMUNE TOLERANCE; RHEUMATOID-ARTHRITIS; MURINE MODEL; FOOD ALLERGY; TNF-ALPHA; IN-VITRO; INDUCTION;
D O I
10.1111/imr.12937
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
B cells have classically been recognized for their unique and indispensable role in the production of antibodies. Their potential as immunoregulatory cells with anti-inflammatory functions has received increasing attention during the last two decades. Herein, we highlight pioneering studies in the field of regulatory B cell (Breg) research. We will review the literature on Bregs with a particular focus on their role in the regulation of allergic inflammation.
引用
收藏
页码:10 / 30
页数:21
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