B cells have classically been recognized for their unique and indispensable role in the production of antibodies. Their potential as immunoregulatory cells with anti-inflammatory functions has received increasing attention during the last two decades. Herein, we highlight pioneering studies in the field of regulatory B cell (Breg) research. We will review the literature on Bregs with a particular focus on their role in the regulation of allergic inflammation.
机构:
Mayo Clin Arizona, Mayo Clin, Grad Sch Biomed Sci, Scottsdale, AZ USAMayo Clin Arizona, Mayo Clin, Grad Sch Biomed Sci, Scottsdale, AZ USA
Jheng, Min-Jhen
Kita, Hirohito
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机构:
Mayo Clin Arizona, Div Allergy Asthma & Clin Immunol, Scottsdale, AZ 85259 USA
Mayo Clin Arizona, Dept Immunol, Scottsdale, AZ 85259 USAMayo Clin Arizona, Mayo Clin, Grad Sch Biomed Sci, Scottsdale, AZ USA