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Molecular characterization of human adenoviruses isolated in Italy
被引:0
作者:
La Rosa, Giuseppina
Muscillo, Michele
Iaconelli, Marcello
Di Grazia, Antonio
Fontana, Stefano
Sali, Michela
De Carolis, Elena
Cattani, Paola
Manzara, Stefania
Fadda, Giovanni
机构:
[1] Ist Super Sanita, Environm & Primary Prevent Dept, Dipartimento Ambiente & Connessa Prevenz Primaria, I-00161 Rome, Italy
[2] Univ Cattolica Sacro Cuore, Ist Microbiol, Policlin A Gemelli, Rome, Italy
关键词:
adenovirus;
epidemiology;
hexon gene;
PCR;
serotyping;
sequencing;
D O I:
暂无
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
There is little information on the epidemiology of Human Adenoviruses (HAdVs) in Italy In this study, 103 HAdV isolates, collected by the A. Gemelli Hospital (Catholic University Medical School of Rome, Italy) between 1987 and 2005, were genotyped by sequencing and phylogenetic analysis on a partial hexon gene region. Nine different serotypes belonging to all six HAdV species were identified. Serotype 2 was the most frequent (53.4%), followed by serotype 1 (15.53%) and serotype 41 (9,7%). Partial-hexon-based identification was confirmed as an effective tool for studying the molecular epidemiology of HAdVs.
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页码:177 / 184
页数:8
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