Preparation and a novel rearrangement reaction of 1,2,3, 4-tetrahydro-9-hydroxy-β-carboline, and their applications for the total synthesis of (±)-coerulescine

被引：24
|
作者：
Somei, M [1 ]
Noguchi, K [1 ]
Yamagami, R [1 ]
Kawada, Y [1 ]
Yamada, K [1 ]
Yamada, F [1 ]
机构：
[1] Kanazawa Univ, Fac Pharmaceut Sci, Kanazawa, Ishikawa 9200934, Japan
来源：
HETEROCYCLES | 2000年 / 53卷 / 01期
关键词：
D O I：
10.3987/COM-99-8743
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Novel 9-hydroxy-beta-carboline derivatives were produced for the first time. A novel rearrangement reaction of 1,2,3,4-tetrahydro-9-hydroxy-beta-carbolines was discovered to give 3,3-disubstituted oxindoles, which was successfully applied to the total synthesis of (+/-)-coerulescine.
引用
收藏
页码：7 / 10
页数：4
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