Breastfeeding protects against adverse respiratory outcomes at 15 months of age

被引:26
作者
Silvers, Karen M. [1 ]
Frampton, Chris M. [1 ]
Wickens, Kristin [3 ]
Epton, Michael J. [1 ]
Pattemore, Philip K. [2 ]
Ingham, Tristram [3 ]
Fishwick, David [5 ]
Crane, Julian [3 ]
Town, G. Ian [4 ]
机构
[1] Univ Otago, Christchurch Sch Med & Hlth Sci, Dept Med, Christchurch, New Zealand
[2] Univ Otago, Christchurch Sch Med & Hlth Sci, Dept Paediat, Christchurch, New Zealand
[3] Univ Otago, Dept Med, Wellington Asthma Res Grp, Wellington Sch Med & Hlth Sci, Wellington, New Zealand
[4] Univ Canterbury, Christchurch 1, New Zealand
[5] Univ Sheffield, Ctr Workplace Hlth, Sheffield, S Yorkshire, England
关键词
breastfeeding; asthma; wheeze; eczema; prospective birth cohort; children; NEW-ZEALAND; ASTHMA; CHILDHOOD; CHILDREN; BIRTH; RISK; SENSITIZATION; ASSOCIATION; PHENOTYPES; RECALL;
D O I
10.1111/j.1740-8709.2008.00169.x
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The relationship between breastfeeding, respiratory and other allergic disorders has been controversial. Our aim was to investigate the relationships between breastfeeding, respiratory outcomes, eczema and atopy at 15 months of age in a prospective birth cohort in New Zealand. A total of 1105 children were enrolled at birth, and 1011 (91.2%) were followed up at 15 months. Logistic regression was used to model associations between breastfeeding duration and respiratory outcomes, eczema and atopy after adjusting for relevant confounding variables: ethnicity, socio-economic status, parity, body mass index, smoking in pregnancy, gender and respiratory infections in the first 3 months of life. Breastfeeding was associated with a significant reduction in the risk of adverse respiratory outcomes at 15 months. After adjustment for confounders, each month of exclusive breastfeeding reduced the risk of doctor-diagnosed asthma by 20% (odds ratio 0.80, 95% confidence interval 0.71 to 0.90), wheezing by 12% (0.88, 0.82 to 0.94) and inhaler use by 14% (0.86, 0.78 to 0.93). Associations for both exclusive and additional breastfeeding durations, and respiratory outcomes remained independently significant when modelled simultaneously. Although independently associated with all respiratory outcomes, adjusting for parental history of allergic disease or maternal history of asthma did not alter our findings. Breastfeeding was not associated with eczema or atopy at 15 months. In conclusion, there was a significant protective effect of breastfeeding on infant wheezing and other adverse respiratory outcomes that may be early indicators of asthma in New Zealand children.
引用
收藏
页码:243 / 250
页数:8
相关论文
共 50 条
[21]   Growth and differentiation factor 15 (GDF15) levels predict adverse respiratory outcomes in premature neonates [J].
Almudares, Faeq ;
Hagan, Joseph ;
Chen, Xinpu ;
Devaraj, Sridevi ;
Moorthy, Bhagavatula ;
Lingappan, Krithika .
PEDIATRIC PULMONOLOGY, 2023, 58 (01) :271-278
[22]   Respiratory outcomes study (RESPOS) for preterm infants at primary school age [J].
Astle, Valerie ;
Broom, Margaret ;
Todd, David A. ;
Charles, Blessy ;
Ringland, Cathy ;
Ciszek, Karen ;
Shadbolt, Bruce .
JOURNAL OF ASTHMA, 2015, 52 (01) :40-45
[23]   Breastfeeding and Infant Temperament at Age Three Months [J].
de Lauzon-Guillain, Blandine ;
Wijndaele, Katrien ;
Clark, Matthew ;
Acerini, Carlo L. ;
Hughes, Ieuan A. ;
Dunger, David B. ;
Wells, Jonathan C. ;
Ong, Ken K. .
PLOS ONE, 2012, 7 (01) :39-45
[24]   Breastfeeding and asthma outcomes at the age of 6 years: The Generation R Study [J].
den Dekker, Herman T. ;
Sonnenschein-van der Voort, Agnes M. M. ;
Jaddoe, Vincent W. V. ;
Reiss, Irwin K. ;
de Jongste, Johan C. ;
Duijts, Liesbeth .
PEDIATRIC ALLERGY AND IMMUNOLOGY, 2016, 27 (05) :486-492
[25]   Breastfeeding protects against infectious diseases during infancy in industrialized countries. A systematic review [J].
Duijts, Liesbeth ;
Ramadhani, Made K. ;
Moll, Henriette A. .
MATERNAL AND CHILD NUTRITION, 2009, 5 (03) :199-210
[26]   Dietary patterns at 6, 15 and 24 months of age are associated with IQ at 8 years of age [J].
Smithers, Lisa G. ;
Golley, Rebecca K. ;
Mittinty, Murthy N. ;
Brazionis, Laima ;
Northstone, Kate ;
Emmett, Pauline ;
Lynch, John W. .
EUROPEAN JOURNAL OF EPIDEMIOLOGY, 2012, 27 (07) :525-535
[27]   Association between postterm pregnancy and adverse growth outcomes in preschool-age children [J].
Tang, Jun ;
Gou, Wanglong ;
Fu, Yuanqing ;
Li, Kelei ;
Guo, Xiaofei ;
Huang, Tao ;
Liu, Huijuan ;
Li, Duo ;
Zheng, Ju-Sheng .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2022, 116 (02) :482-490
[28]   Breastfeeding Protects Against Hip Fracture in Postmenopausal Women: The Tromso Study [J].
Bjornerem, Ashild ;
Ahmed, Luai A. ;
Jorgensen, Lone ;
Stormer, Jan ;
Joakimsen, Ragnar M. .
JOURNAL OF BONE AND MINERAL RESEARCH, 2011, 26 (12) :2843-2850
[29]   The Association Between Type of Supplementation in the Newborn Nursery and Breastfeeding Outcomes at 2 and 6 Months of Age [J].
Gray, Karin ;
Ryan, Stephanie ;
Churchill, Martha ;
Harder, Valerie S. .
JOURNAL OF HUMAN LACTATION, 2023, 39 (02) :245-254
[30]   Breastfeeding during the first 6 months of life, adiposity rebound and overweight/obesity at 8 years of age [J].
Estevez-Gonzalez, M. D. ;
Santana del Pino, A. ;
Henriquez-Sanchez, P. ;
Pena-Quintana, L. ;
Saavedra-Santana, P. .
INTERNATIONAL JOURNAL OF OBESITY, 2016, 40 (01) :10-13