MnII-containing coordination nanoparticles as highly efficient T1 contrast agents for magnetic resonance imaging

被引：35

作者：

Paul, Gabriella ^{[1
]}

Prado, Yoann ^{[1
]}

Dia, Nada ^{[1
,2
]}

Riviere, Eric ^{[1
]}

Laurent, Sophie ^{[3
,4
]}

Roch, Mathieu ^{[5
]}

Vander Elst, Luce ^{[3
,4
,5
]}

Muller, Robert N. ^{[3
,4
,5
]}

Sancey, Lucie ^{[6
]}

Perriat, Pascal ^{[7
]}

Tillement, Olivier ^{[6
]}

Mallah, Talal ^{[1
]}

Catala, Laure ^{[1
]}

机构：

[1] Univ Paris 11, CNRS, Inst Chim Mol & Mat Orsay, F-91405 Orsay, France

[2] Univ Libanaise, Ecole Doctorale Sci & Technol, Beirut, Lebanon

[3] Univ Mons, NMR, B-7000 Mons, Belgium

[4] Univ Mons, Dept Gen Organ & Biomed Chem, Mol Imaging Lab, B-7000 Mons, Belgium

[5] Ctr Microscopy & Mol Imaging, B-6041 Gosselies, Belgium

[6] Univ Lyon 1, CNRS, Inst Lumiere Mat Equipe FENNEC, UMR 5306, F-69622 Villeurbanne, France

[7] INSA Lyon, F-69621 Villeurbanne, France

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 51期

关键词：

METAL-ORGANIC FRAMEWORKS; GOLD NANOPARTICLES; HIGH-RELAXIVITY; MRI;

D O I：

10.1039/c4cc01251h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Large longitudinal relaxivities were observed in Mn-II-containing Prussian blue analogue nanoparticles. At low concentrations and high field (7 T), a remarkable positive contrast enhancement was seen which exceeded that of clinical contrast agents and was attributed to the very large proportion of surface atoms of these coordination nanoparticles.

引用

页码：6740 / 6743

页数：4

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