MnII-containing coordination nanoparticles as highly efficient T1 contrast agents for magnetic resonance imaging

被引：34
作者：
Paul, Gabriella [1 ]
Prado, Yoann [1 ]
Dia, Nada [1 ,2 ]
Riviere, Eric [1 ]
Laurent, Sophie [3 ,4 ]
Roch, Mathieu [5 ]
Vander Elst, Luce [3 ,4 ,5 ]
Muller, Robert N. [3 ,4 ,5 ]
Sancey, Lucie [6 ]
Perriat, Pascal [7 ]
Tillement, Olivier [6 ]
Mallah, Talal [1 ]
Catala, Laure [1 ]
机构：
[1] Univ Paris 11, CNRS, Inst Chim Mol & Mat Orsay, F-91405 Orsay, France
[2] Univ Libanaise, Ecole Doctorale Sci & Technol, Beirut, Lebanon
[3] Univ Mons, NMR, B-7000 Mons, Belgium
[4] Univ Mons, Dept Gen Organ & Biomed Chem, Mol Imaging Lab, B-7000 Mons, Belgium
[5] Ctr Microscopy & Mol Imaging, B-6041 Gosselies, Belgium
[6] Univ Lyon 1, CNRS, Inst Lumiere Mat Equipe FENNEC, UMR 5306, F-69622 Villeurbanne, France
[7] INSA Lyon, F-69621 Villeurbanne, France
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 51期
关键词：
METAL-ORGANIC FRAMEWORKS; GOLD NANOPARTICLES; HIGH-RELAXIVITY; MRI;
D O I：
10.1039/c4cc01251h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Large longitudinal relaxivities were observed in Mn-II-containing Prussian blue analogue nanoparticles. At low concentrations and high field (7 T), a remarkable positive contrast enhancement was seen which exceeded that of clinical contrast agents and was attributed to the very large proportion of surface atoms of these coordination nanoparticles.
引用
收藏
页码：6740 / 6743
页数：4
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