Influence of testosterone gel treatment on spermatogenesis in men with hypogonadism

被引：5

作者：

George, Mskhalaya ^{[1
]}

Yulia, Tishova ^{[2
]}

Svetlana, Kalinchenko ^{[2
]}

机构：

[1] Ctr Reprod Med MAMA, Androl & Endocrinol Dept, Moscow, Russia

[2] Peoples Friendship Univ Russia, Dept Endocrinol, Moscow, Russia

来源：

GYNECOLOGICAL ENDOCRINOLOGY | 2014年 / 30卷

关键词：

Androgel; androgen deficiency; hypogonadism; sperm; spermatogenesis; testosterone; testosterone gel; OBESITY EPIDEMIC; PHARMACOKINETICS; PREVALENCE;

D O I：

10.3109/09513590.2014.945777

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The prevalence of androgen deficiency in reproductive-aged men is increasing and needs new approach to long-term hypogonadism treatment that can preserve fertility. An open non-controlled pilot study included 18 men with eugonadotropic hypogonadism, who received transdermal testosterone gel treatment for 3 months. Sperm analysis was made before treatment and after 3 month of testosterone therapy. Testosterone level was normalized in all patients, but no negative effect was observed on spermatogenesis. Testosterone gel therapy may be a therapy of choice in hypogonadal men of reproductive age but further studies are needed.

引用

页码：22 / 24

页数：3