Influence of testosterone gel treatment on spermatogenesis in men with hypogonadism

被引：5
作者：
George, Mskhalaya [1 ]
Yulia, Tishova [2 ]
Svetlana, Kalinchenko [2 ]
机构：
[1] Ctr Reprod Med MAMA, Androl & Endocrinol Dept, Moscow, Russia
[2] Peoples Friendship Univ Russia, Dept Endocrinol, Moscow, Russia
来源：
GYNECOLOGICAL ENDOCRINOLOGY | 2014年 / 30卷
关键词：
Androgel; androgen deficiency; hypogonadism; sperm; spermatogenesis; testosterone; testosterone gel; OBESITY EPIDEMIC; PHARMACOKINETICS; PREVALENCE;
D O I：
10.3109/09513590.2014.945777
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The prevalence of androgen deficiency in reproductive-aged men is increasing and needs new approach to long-term hypogonadism treatment that can preserve fertility. An open non-controlled pilot study included 18 men with eugonadotropic hypogonadism, who received transdermal testosterone gel treatment for 3 months. Sperm analysis was made before treatment and after 3 month of testosterone therapy. Testosterone level was normalized in all patients, but no negative effect was observed on spermatogenesis. Testosterone gel therapy may be a therapy of choice in hypogonadal men of reproductive age but further studies are needed.
引用
收藏
页码：22 / 24
页数：3
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