Mean Platelet Volume in Recurrent Aphthous Stomatitis and Behcet Disease

被引:66
作者
Ekiz, Ozlem [1 ]
Balta, Ilknur [2 ]
Sen, Bilge Bulbul [1 ]
Rifaioglu, Emine Nur [1 ]
Ergin, Can [3 ]
Balta, Sevket [4 ]
Demirkol, Sait [4 ]
机构
[1] Mustafa Kemal Univ, Sch Med, Dept Dermatol, Antakya, Turkey
[2] Ankara Kecioren Training & Res Hosp, Dept Dermatol, Ankara, Turkey
[3] Ankara Diskapi Yildirim Beyazit Training & Res Ho, Dept Dernatol, Ankara, Turkey
[4] Gulhane Mil Med Acad, Dept Cardiol, Ankara, Turkey
关键词
Behcet disease; mean platelet volume; recurrent aphthous stomatitis; vascular; INFLAMMATORY-BOWEL-DISEASE; ANKYLOSING-SPONDYLITIS; ACTIVATION; MARKER; BLOOD; INTERLEUKIN-6; ENDOTHELIN-1; ASSOCIATION; STATE; LINK;
D O I
10.1177/0003319713492375
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Behcet disease (BD) and recurrent aphthous stomatitis (RAS) are systemic inflammatory diseases, but the exact pathogenesis of both the diseases is unknown. Mean platelet volume (MPV) is an indicator of platelet activation. The aim of this study was to investigate the MPV levels in patients with BD, RAS, and healthy participants. A total of 61 patients with BD, 60 patients with RAS, and 60 healthy controls were included in this study. The MPV levels and erythrocyte sedimentation rate in patients with BD and RAS groups were significantly higher than the control groups (P < .001). In the BD group as well as in the RAS group, the disease activity does not affect the levels of MPV. The MPV levels may be used as a cheap and feasible diagnostic marker in patients with BD and RAS. Nevertheless, the MPV does not have a predictive value in differentiating the diagnosis of BD and RAS.
引用
收藏
页码:161 / 165
页数:5
相关论文
共 37 条
[11]  
Criteria for diagnosis of Behcet's disease, 1990, Lancet, V335, P1078
[12]   Behcet's disease: from east to west [J].
Davatchi, Fereydoun ;
Shahram, Farhad ;
Chams-Davatchi, Cheyda ;
Shams, Hormoz ;
Nadji, Abdolhadi ;
Akhlaghi, Massoomeh ;
Faezi, Tahereh ;
Ghodsi, Zahra ;
Faridar, Alireza ;
Ashofteh, Farima ;
Abdollahi, Bahar Sadeghi .
CLINICAL RHEUMATOLOGY, 2010, 29 (08) :823-833
[13]   Evaluation of the mean platelet volume in patients with cardiac syndrome X [J].
Demirkol, Sait ;
Balta, Sevket ;
Unlu, Murat ;
Yuksel, Uygar Cagdas ;
Celik, Turgay ;
Arslan, Zekeriya ;
Kucuk, Ugur ;
Yokusoglu, Mehmet .
CLINICS, 2012, 67 (09) :1019-1022
[14]  
Ekiz F, 2012, CLIN APPL THROMB HEM
[15]   Mean Platelet Volume as a Fibrosis Marker in Patients With Chronic Hepatitis B [J].
Ekiz, Fuat ;
Yuksel, Osman ;
Kocak, Erdem ;
Yilmaz, Baris ;
Altinbas, Akif ;
Coban, Sahin ;
Yuksel, Ilhami ;
Uskudar, Oguz ;
Koklu, Seyfettin .
JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2011, 25 (03) :162-165
[16]   Platelet soluble CD40L and matrix metalloproteinase 9 activity are proinflammatory mediators in Behcet disease patients [J].
Fernandez Bello, Ihosvany ;
Alvarez, Maria T. ;
Lopez-Longo, Francisco J. ;
Arias-Salgado, Elena G. ;
Martin, Monica ;
Jimenez-Yuste, Victor ;
Rodriguez de la Rua, Ana ;
Butta, Nora V. .
THROMBOSIS AND HAEMOSTASIS, 2012, 107 (01) :88-98
[17]  
Gasparyan AY, 2011, CURR PHARM DESIGN, V17, P47
[18]  
Gasparyan Armen Yuri, 2010, Inflammation & Allergy Drug Targets, V9, P45
[19]   Behcet's disease and complex aphthosis [J].
Ghate, JV ;
Jorizzo, JL .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1999, 40 (01) :1-18
[20]   Cytokine profile in Behcet's disease patients - Relationship with disease activity [J].
Hamzaoui, K ;
Hamzaoui, A ;
Guemira, F ;
Bessioud, M ;
Hamza, M ;
Ayed, K .
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, 2002, 31 (04) :205-210