Epigenetic traits of testicular cancer: from primordial germ cells to germ cell tumors

被引:0
作者
del Mazo, Jesus [1 ]
Garcia-Lopez, Jesus [1 ]
Weber, Michael [2 ]
机构
[1] Ctr Invest Biol CIB CSIC, Madrid 28040, Spain
[2] Univ Strasbourg, CNRS UMR7242, F-67412 Illkirch Graffenstaden, France
关键词
carcinoma in situ; DNA methylation; endocrine disruptors; epigenetics; histone code; miRNAs; piRNAs; primordial germ cells; testicular cancer; ENDOCRINE DISRUPTORS; METHYLATION; GENOME; MECHANISMS; DYNAMICS; ERASURE;
D O I
10.2217/EPI.14.24
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
引用
收藏
页码:253 / 255
页数:3
相关论文
共 22 条
[1]   Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells [J].
Almstrup, K. ;
Nielsen, J. E. ;
Mlynarska, O. ;
Jansen, M. T. ;
Jorgensen, A. ;
Skakkebaek, N. E. ;
Rajpert-De Meyts, E. .
BRITISH JOURNAL OF CANCER, 2010, 103 (08) :1269-1276
[2]   Endocrine disruptors, gene deregulation and male germ cell tumors [J].
Del Mazo, Jesus ;
Brieno-Enriquez, Miguel A. ;
Garcia-Lopez, Jesus ;
Lopez-Fernandez, Luis A. ;
De Felici, Massimo .
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, 2013, 57 (2-4) :225-239
[3]   DNA methylation changes during mouse spermatogenesis [J].
del Mazo, Jesus ;
Prantera, Giorgio ;
Torres, Miguel ;
Ferraro, Marina .
CHROMOSOME RESEARCH, 1994, 2 (02) :147-152
[4]   Multiple Epigenetic Mechanisms and the piRNA Pathway Enforce LINE1 Silencing during Adult Spermatogenesis [J].
Di Giacomo, Monica ;
Comazzetto, Stefano ;
Saini, Harpreet ;
De Fazio, Serena ;
Carrieri, Claudia ;
Morgan, Marcos ;
Vasiliauskaite, Lina ;
Benes, Vladimir ;
Enright, Anton J. ;
O'Carroll, Donal .
MOLECULAR CELL, 2013, 50 (04) :601-608
[5]   Turning germ cells into stem cells [J].
Donovan, PJ ;
de Miguel, MP .
CURRENT OPINION IN GENETICS & DEVELOPMENT, 2003, 13 (05) :463-471
[6]   Epigenetic loss of the PIWI/piRNA machinery in human testicular tumorigenesis [J].
Ferreira, Humberto J. ;
Heyn, Holger ;
Garcia del Muro, Xavier ;
Vidal, August ;
Larriba, Sara ;
Munoz, Clara ;
Villanueva, Alberto ;
Esteller, Manel .
EPIGENETICS, 2014, 9 (01) :113-118
[7]   MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks [J].
Fraser, Michael ;
Harding, Shane M. ;
Zhao, Helen ;
Coackley, Carla ;
Durocher, Daniel ;
Bristow, Robert G. .
CELL CYCLE, 2011, 10 (13) :2218-2232
[8]  
Garcia-Lopez Jesus, 2013, Biomol Concepts, V4, P367, DOI 10.1515/bmc-2013-0015
[9]   Expression and interdependencies of pluripotency factors LIN28, OCT3/4, NANOG and SOX2 in human testicular germ cells and tumours of the testis [J].
Gillis, A. J. M. ;
Stoop, H. ;
Biermann, K. ;
van Gurp, R. J. H. L. M. ;
Swartzman, E. ;
Cribbes, S. ;
Ferlinz, A. ;
Shannon, M. ;
Oosterhuis, J. W. ;
Looijenga, L. H. J. .
INTERNATIONAL JOURNAL OF ANDROLOGY, 2011, 34 (04) :E160-E174
[10]   Global profiling of DNA methylation erasure in mouse primordial germ cells [J].
Guibert, Sylvain ;
Forne, Thierry ;
Weber, Michael .
GENOME RESEARCH, 2012, 22 (04) :633-641