An Efficient Synthesis of 4-Arylmethylidene-3-substituted-Isoxazol-5(4H)-ones in Aqueous Medium

被引：28

作者：

Chavan, Abhijit P. ^{[1
]}

Pinjari, Avinash B. ^{[1
]}

Mhaske, Pravin C. ^{[1
]}

机构：

[1] Univ Pune, Sir Parashurambahu Coll, Post Grad Dept Chem, Pune 411030, Maharashtra, India

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2015年 / 52卷 / 06期

关键词：

Multi-component reactions; catalyst free; water; isoxazol-5(4H)-ones; -keto-ester; ONE-POT SYNTHESIS; ORGANIC-REACTIONS; 3-METHYL-4-ARYLMETHYLENE-ISOXAZOL-5(4H)-ONES; ISOXAZOLONE; INHIBITORS; SERIES; WATER; CONDENSATION; DERIVATIVES; ALDEHYDES;

D O I：

10.1002/jhet.2293

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 4-arylmethylidene-3-substituted-isoxazol-5(4H)-ones were efficiently synthesized by eco-benign, one pot uncatalyzed reaction of -keto-ester, hydroxylamine hydrochloride, and aromatic aldehyde with electron donating substituent in water.

引用

页码：1911 / 1915

页数：5

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