Selective blockade of estrogen receptor beta improves wound healing in diabetes

被引:7
作者
Sunkari, Vivekananda Gupta [1 ]
Botusan, Ileana R. [1 ,2 ]
Savu, Octavian [1 ,3 ]
Grunler, Jacob [1 ]
Zheng, Xiaowei [1 ]
Gustafsson, Jan-Ake [4 ]
Brismar, Kerstin [1 ]
Catrina, Sergiu-Bogdan [1 ]
机构
[1] Karolinska Univ Hosp Solna, Rolf Luft Res Ctr Diabet & Endocrinol, Karolinska Inst, Dept Mol Med & Surg, S-17176 Stockholm, Sweden
[2] Univ Med & Pharm Carol Davila, Dept Endocrinol, Bucharest, Romania
[3] Natl Inst Diabet NC Paulescu, Bucharest, Romania
[4] Karolinska Inst, Dept Biosci & Nutr, Stockholm, Sweden
关键词
HIF-1-ALPHA;
D O I
10.1007/s12020-013-0144-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:347 / 350
页数:4
相关论文
共 10 条
[1]   Impaired TGF-β signaling and a defect in resolution of inflammation contribute to delayed wound healing in a female rat model of type 2 diabetes [J].
Al-Mulla, Fahd ;
Leibovich, Samuel J. ;
Francis, Issam M. ;
Bitar, Milad S. .
MOLECULAR BIOSYSTEMS, 2011, 7 (11) :3006-3020
[2]   Diagnostics and treatment of the diabetic foot [J].
Apelqvist, Jan .
ENDOCRINE, 2012, 41 (03) :384-397
[3]   Estrogen Receptors and Endothelium [J].
Arnal, Jean-Francois ;
Fontaine, Coralie ;
Billon-Gales, Audrey ;
Favre, Julie ;
Laurell, Henrik ;
Lenfant, Francoise ;
Gourdy, Pierre .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2010, 30 (08) :1506-1512
[4]   Topical estrogen accelerates cutaneous wound healing in aged humans associated with an altered inflammatory response [J].
Ashcroft, GS ;
Greenwell-Wild, T ;
Horan, MA ;
Wahl, SM ;
Ferguson, MWJ .
AMERICAN JOURNAL OF PATHOLOGY, 1999, 155 (04) :1137-1146
[5]   Estrogen accelerates cutaneous wound healing associated with an increase in TGF-beta 1 levels [J].
Ashcroft, GS ;
Dodsworth, J ;
vanBoxtel, E ;
Tarnuzzer, RW ;
Horan, MA ;
Schultz, GS ;
Ferguson, MWJ .
NATURE MEDICINE, 1997, 3 (11) :1209-1215
[6]   Stabilization of HIF-1α is critical to improve wound healing in diabetic mice [J].
Botusan, Ileana Ruxandra ;
Sunkari, Vivekananda Gupta ;
Savu, Octavian ;
Catrina, Anca Irinel ;
Grunler, Jacob ;
Lindberg, Stina ;
Pereira, Teresa ;
Yla-Herttuala, Seppo ;
Poellinger, Lorenz ;
Brismar, Kerstin ;
Catrina, Sergiu-Bogdan .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (49) :19426-19431
[7]   Estrogen promotes cutaneous wound healing via estrogen receptor β independent of its antiinflammatory activities [J].
Campbell, Laura ;
Emmerson, Elaine ;
Davies, Faith ;
Gilliver, Stephen C. ;
Krust, Andre ;
Chambon, Pierre ;
Ashcroft, Gillian S. ;
Hardman, Matthew J. .
JOURNAL OF EXPERIMENTAL MEDICINE, 2010, 207 (09) :1825-1833
[8]   β-LGND2, an ERβ Selective Agonist, Inhibits Pathologic Retinal Neovascularization [J].
Giddabasappa, Anand ;
Eswaraka, Jeetendra R. ;
Barrett, Christina M. ;
Bauler, Matthew N. ;
Wu, Zhongzhi ;
Yepuru, Muralimohan ;
Miller, Duane D. ;
Dalton, James T. .
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2012, 53 (08) :5066-5075
[9]   17β-Estradiol Antagonizes the Down-Regulation of ERα/NOS-3 Signaling in Vascular Endothelial Dysfunction of Female Diabetic Rats [J].
Han, Yi ;
Li, Xiaozhen ;
Zhou, Suming ;
Meng, Guoliang ;
Xiao, Yujiao ;
Zhang, Wen ;
Wang, Zhuoying ;
Xie, Liping ;
Liu, Zhen ;
Lu, Hui ;
Ji, Yong .
PLOS ONE, 2012, 7 (11)
[10]   ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading [J].
Mak, Paul ;
Leav, Irwin ;
Pursell, Bryan ;
Bae, Donggoo ;
Yang, Xiaofang ;
Taglienti, Cherie A. ;
Gouvin, Lindsey M. ;
Sharma, Vishva M. ;
Mercurio, Arthur M. .
CANCER CELL, 2010, 17 (04) :319-332