Flumazenil positron emission tomography and other ligands for functional imaging

被引：25
作者：
Hammers, A
机构：
[1] UCL, Dept Clin & Expt Epilepsy, Inst Neurol, London WC1N 3BG, England
[2] Univ London Imperial Coll Sci & Technol, Dept PET Neurosci, MRC Clin Sci Ctr, London W12 0NN, England
来源：
NEUROIMAGING CLINICS OF NORTH AMERICA | 2004年 / 14卷 / 03期
关键词：
D O I：
10.1016/j.nic.2004.04.012
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Positron emission tomography (PET) enables tomographic imaging of local concentrations of injected biologically active substances that have been radioactively labeled (radioligands; tracers). Patients can be investigated in the resting state or in relationship to an event (eg, injection of a drug or occurrence of a seizure). This article discusses the use of flumazenil PET and other ligands in focal and idiopathic generalized epilepsies.
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页码：537 / +
页数：16
相关论文
共 96 条
[1]  
[Anonymous], PET GRUNDLAGEN ANWEN
[2]   Positron emission tomography partial volume correction: Estimation and algorithms [J].
Aston, JAD ;
Cunningham, VJ ;
Asselin, MC ;
Hammers, A ;
Evans, AC ;
Gunn, RN .
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2002, 22 (08) :1019-1034
[3]   [11C](R)-PK11195 positron emission tomography imaging of activated microglia in vivo in Rasmussen's encephalitis [J].
Banati, RB ;
Goerres, GW ;
Myers, R ;
Gunn, RN ;
Turkheimer, FE ;
Kreutzberg, GW ;
Brooks, DJ ;
Jones, T ;
Duncan, JS .
NEUROLOGY, 1999, 53 (09) :2199-2203
[4]   Long-term trans-synaptic glial responses in the human thalamus after peripheral nerve injury [J].
Banati, RB ;
Cagnin, A ;
Brooks, DJ ;
Gunn, RN ;
Myers, R ;
Jones, T ;
Birch, R ;
Anand, P .
NEUROREPORT, 2001, 12 (16) :3439-3442
[5]   The peripheral benzodiazepine binding site in the brain in multiple sclerosis -: Quantitative in vivo imaging of microglia as a measure of disease activity [J].
Banati, RB ;
Newcombe, J ;
Gunn, RN ;
Cagnin, A ;
Turkheimer, F ;
Heppner, F ;
Price, G ;
Wegner, F ;
Giovannoni, G ;
Miller, DH ;
Perkin, GD ;
Smith, T ;
Hewson, AK ;
Bydder, G ;
Kreutzberg, GW ;
Jones, T ;
Cuzner, ML ;
Myers, R .
BRAIN, 2000, 123 :2321-2337
[6]  
Barkovich AJ, 1997, EPILEPSIA, V38, P1255
[7]   INVESTIGATION OF THE OPIOID SYSTEM IN ABSENCE SEIZURES WITH POSITRON EMISSION TOMOGRAPHY [J].
BARTENSTEIN, PA ;
DUNCAN, JS ;
PREVETT, MC ;
CUNNINGHAM, VJ ;
FISH, DR ;
JONES, AKP ;
LUTHRA, SK ;
SAWLE, GV ;
BROOKS, DJ .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1993, 56 (12) :1295-1302
[8]   QUANTIFICATION OF OPIATE RECEPTORS IN 2 PATIENTS WITH MESIOBASAL TEMPORAL-LOBE EPILEPSY, BEFORE AND AFTER SELECTIVE AMYGDALO-HIPPOCAMPECTOMY, USING POSITRON EMISSION TOMOGRAPHY [J].
BARTENSTEIN, PA ;
PREVETT, MC ;
DUNCAN, JS ;
HAJEK, M ;
WIESER, HG .
EPILEPSY RESEARCH, 1994, 18 (02) :119-125
[9]  
Berkovich AJ, 1998, EPILEPSIA, V39, P1375
[10]   TEMPORAL-LOBE CENTRAL BENZODIAZEPINE BINDING IN UNILATERAL MESIAL TEMPORAL-LOBE EPILEPSY [J].
BURDETTE, DE ;
SAKURAI, SY ;
HENRY, TR ;
ROSS, DA ;
PENNELL, PB ;
FREY, KA ;
SACKELLARES, JC ;
ALBIN, RL .
NEUROLOGY, 1995, 45 (05) :934-941
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