Substantial genetic influence on cognitive abilities in twins 80 or more years old

被引:535
作者
McClearn, GE
Johansson, B
Berg, S
Pedersen, NL
Ahern, F
Petrill, SA
Plomin, R
机构
[1] INST PSYCHIAT,SOCIAL GENET & DEV PSYCHIAT RES CTR,LONDON SE5 8AF,ENGLAND
[2] KAROLINSKA INST,INST ENVIRONM MED,S-17177 STOCKHOLM,SWEDEN
[3] UNIV COLL HLTH SCI,INST GERONTOL,S-55111 JONKOPING,SWEDEN
[4] PENN STATE UNIV,CTR DEV & HLTH GENET,UNIVERSITY PK,PA 16802
关键词
D O I
10.1126/science.276.5318.1560
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
General and specific cognitive abilities were studied in intact Swedish same-sex twin pairs 80 or more years old for whom neither twin had major cognitive, sensory, or motor impairment. Resemblance for 110 identical twin pairs significantly exceeded resemblance for 130 fraternal same-sex twin pairs for all abilities. Maximum-likelihood model-fitting estimates of heritability were 62 percent for general cognitive ability, 55 percent for verbal ability, 32 percent for spatial ability, 62 percent for speed of processing, and 52 percent for memory, There was also evidence for the significant influence of idiosyncratic experience as the environmental component that most determines individual differences in cognitive abilities late in life.
引用
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页码:1560 / 1563
页数:6
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