Bioprinting for the Biologist

被引:241
作者
Daly, Andrew C. [1 ]
Prendergast, Margaret E. [1 ]
Hughes, Alex J. [1 ,2 ]
Burdick, Jason A. [1 ]
机构
[1] Univ Penn, Dept Bioengn, Philadelphia, PA 19104 USA
[2] Univ Penn, Dept Cell & Dev Biol, Philadelphia, PA 19104 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
PLANAR CELL POLARITY; IN-VITRO; COLLECTIVE MIGRATION; SELF-ORGANIZATION; STEM-CELL; TISSUE; HYDROGELS; MODEL; GENERATION; GRADIENTS;
D O I
10.1016/j.cell.2020.12.002
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Building tissues from scratch to explore entirely new cell configurations could revolutionize fundamental understanding in biology. Bioprinting is an emerging technology to do this. Although typically applied to engineer tissues for therapeutic tissue repair or drug screening, there are many opportunities for bioprinting within biology, such as for exploring cellular crosstalk or cellular morphogenesis. The overall goals of this Primer are to provide an overview of bioprinting with the biologist in mind, outline the steps in extrusion bioprinting (the most widely used and accessible technology), and discuss alternative bioprinting technologies and future opportunities for bioprinting in biology.
引用
收藏
页码:18 / 32
页数:15
相关论文
共 88 条
[1]   Methylcellulose - a versatile printing material that enables biofabrication of tissue equivalents with high shape fidelity [J].
Ahlfeld, T. ;
Guduric, V. ;
Duin, S. ;
Akkineni, A. R. ;
Schuetz, K. ;
Kilian, D. ;
Emmermacher, J. ;
Cubo-Mateo, N. ;
Dani, S. ;
Witzleben, M. v. ;
Spangenberg, J. ;
Abdelgaber, R. ;
Richter, R. F. ;
Lode, A. ;
Gelinsky, M. .
BIOMATERIALS SCIENCE, 2020, 8 (08) :2102-2110
[2]   Synthetic alternatives to Matrigel [J].
Aisenbrey, Elizabeth A. ;
Murphy, William L. .
NATURE REVIEWS MATERIALS, 2020, 5 (07) :539-551
[3]   Morphogenesis of epithelial tubes: Insights into tube formation, elongation, and elaboration [J].
Andrew, Deborah J. ;
Ewald, Andrew J. .
DEVELOPMENTAL BIOLOGY, 2010, 341 (01) :34-55
[4]   Transient Tissue-Scale Deformation Coordinates Alignment of Planar Cell Polarity Junctions in the Mammalian Skin [J].
Aw, Wen Yih ;
Heck, Bryan W. ;
Joyce, Bradley ;
Devenport, Danelle .
CURRENT BIOLOGY, 2016, 26 (16) :2090-2100
[5]   Aspiration-assisted bioprinting for precise positioning of biologics [J].
Ayan, Bugra ;
Heo, Dong Nyoung ;
Zhang, Zhifeng ;
Dey, Madhuri ;
Povilianskas, Adomas ;
Drapaca, Corina ;
Ozbolat, Ibrahim T. .
SCIENCE ADVANCES, 2020, 6 (10)
[6]   Making data matter: Voxel printing for the digital fabrication of data across scales and domains [J].
Bader, Christoph ;
Kolb, Dominik ;
Weaver, James C. ;
Sharma, Sunanda ;
Hosny, Ahmed ;
Costa, Joao ;
Oxman, Neri .
SCIENCE ADVANCES, 2018, 4 (05)
[7]   Engineered In Vitro Disease Models [J].
Benam, Kambez H. ;
Dauth, Stephanie ;
Hassell, Bryan ;
Herland, Anna ;
Jain, Abhishek ;
Jang, Kyung-Jin ;
Karalis, Katia ;
Kim, Hyun Jung ;
MacQueen, Luke ;
Mahmoodian, Roza ;
Musah, Samira ;
Torisawa, Yu-suke ;
van der Meer, Andries D. ;
Villenave, Remi ;
Yadid, Moran ;
Parker, Kevin K. ;
Ingber, Donald E. .
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 10, 2015, 10 :195-262
[8]   Volumetric Bioprinting of Complex Living-Tissue Constructs within Seconds [J].
Bernal, Paulina Nunez ;
Delrot, Paul ;
Loterie, Damien ;
Li, Yang ;
Malda, Jos ;
Moser, Christophe ;
Levato, Riccardo .
ADVANCED MATERIALS, 2019, 31 (42)
[9]   Thiol-Ene Clickable Gelatin: A Platform Bioink for Multiple 3D Biofabrication Technologies [J].
Bertlein, Sarah ;
Brown, Gabriella ;
Lim, Khoon S. ;
Jungst, Tomasz ;
Boeck, Thomas ;
Blunk, Torsten ;
Tessmar, Joerg ;
Hooper, Gary J. ;
Woodfield, Tim B. F. ;
Groll, Juergen .
ADVANCED MATERIALS, 2017, 29 (44)
[10]   Writing in the granular gel medium [J].
Bhattacharjee, Tapomoy ;
Zehnder, Steven M. ;
Rowe, Kyle G. ;
Jain, Suhani ;
Nixon, Ryan M. ;
Sawyer, W. Gregory ;
Angelini, Thomas E. .
SCIENCE ADVANCES, 2015, 1 (08)