Bioprinting for the Biologist

被引:219
作者
Daly, Andrew C. [1 ]
Prendergast, Margaret E. [1 ]
Hughes, Alex J. [1 ,2 ]
Burdick, Jason A. [1 ]
机构
[1] Univ Penn, Dept Bioengn, Philadelphia, PA 19104 USA
[2] Univ Penn, Dept Cell & Dev Biol, Philadelphia, PA 19104 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
PLANAR CELL POLARITY; IN-VITRO; COLLECTIVE MIGRATION; SELF-ORGANIZATION; STEM-CELL; TISSUE; HYDROGELS; MODEL; GENERATION; GRADIENTS;
D O I
10.1016/j.cell.2020.12.002
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Building tissues from scratch to explore entirely new cell configurations could revolutionize fundamental understanding in biology. Bioprinting is an emerging technology to do this. Although typically applied to engineer tissues for therapeutic tissue repair or drug screening, there are many opportunities for bioprinting within biology, such as for exploring cellular crosstalk or cellular morphogenesis. The overall goals of this Primer are to provide an overview of bioprinting with the biologist in mind, outline the steps in extrusion bioprinting (the most widely used and accessible technology), and discuss alternative bioprinting technologies and future opportunities for bioprinting in biology.
引用
收藏
页码:18 / 32
页数:15
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