Comparison of Opioid Prescribing by Dentists in the United States and England

被引:74
作者
Suda, Katie J. [1 ,2 ]
Durkin, Michael J. [3 ]
Calip, Gregory S. [2 ]
Gellad, Walid F. [4 ,5 ]
Kim, Hajwa [6 ]
Lockhart, Peter B. [7 ]
Rowan, Susan A. [8 ]
Thornhill, Martin H. [7 ,9 ]
机构
[1] Edward Hines Jr VA Hosp, Ctr Innovat Complex Chron Healthcare, Chicago, IL USA
[2] Univ Illinois, Coll Pharm, Chicago, IL USA
[3] Washington Univ, Sch Med, St Louis, MO USA
[4] Pittsburgh Vet Adm Healthcare Syst, Ctr Hlth Equ Res & Promot, Pittsburgh, PA USA
[5] Univ Pittsburgh, Sch Med, Pittsburgh, PA USA
[6] Univ Illinois, Ctr Clin & Translat Sci, Chicago, IL USA
[7] Carolinas Med Ctr, Dept Oral Med, Charlotte, NC 28203 USA
[8] Univ Illinois, Coll Dent, Chicago, IL USA
[9] Univ Sheffield, Sch Clin Dent, Sheffield, S Yorkshire, England
基金
美国医疗保健研究与质量局; 美国国家卫生研究院;
关键词
PAIN;
D O I
10.1001/jamanetworkopen.2019.4303
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
IMPORTANCE The United States consumes most of the opioids worldwide despite representing a small portion of the world's population. Dentists are one of the most frequent US prescribers of opioids despite data suggesting that nonopioid analgesics are similarly effective for oral pain. While oral health and dentist use are generally similar between the United States and England, it is unclear how opioid prescribing by dentists varies between the 2 countries. OBJECTIVE To compare opioid prescribing by dentists in the United States and England. DESIGN, SETTING, AND PARTICIPANTS Cross-sectional study of prescriptions for opioids dispensed from outpatient pharmacies and health care settings between January 1 and December 31, 2016, by dentists in the United States and England. Data were analyzed from October 2018 to January 2019. EXPOSURES Opioids prescribed by dentists. MAIN OUTCOMES AND MEASURES Proportion and prescribing rates of opioid prescriptions. RESULTS In 2016, the proportion of prescriptions written by US dentists that were for opioids was 37 times greater than the proportion written by English dentists. In all, 22.3% of US dental prescriptions were opioids (11.4 million prescriptions) compared with 0.6% of English dental prescriptions (28 082 prescriptions) (difference, 21.7%; 95% CI, 13.8%-32.1%; P < .001). Dentists in the United States also had a higher number of opioid prescriptions per 1000 population (35.4 per 1000 US population [95% CI, 25.2-48.7 per 1000 population] vs 0.5 per 1000 England population [95% CI, 0.03-3.7 per 1000 population]) and number of opioid prescriptions per dentist (58.2 prescriptions per dentist [95% CI, 44.9-75.0 prescriptions per dentist] vs 1.2 prescriptions per dentist [95% CI, 0.2-5.6 prescriptions per dentist]). While the codeine derivative dihydrocodeine was the sole opioid prescribed by English dentists, US dentists prescribed a range of opioids containing hydrocodone (62.3%), codeine (23.2%), oxycodone (9.1%), and tramadol (4.8%). Dentists in the United States also prescribed long-acting opioids (0.06% of opioids prescribed by US dentists [6425 prescriptions]). Long-acting opioids were not prescribed by English dentists. CONCLUSIONS AND RELEVANCE This study found that in 2016, dentists in the United States prescribed opioids with significantly greater frequency than their English counterparts. Opioids with a high potential for abuse, such as oxycodone, were frequently prescribed by US dentists but not prescribed in England. These results illustrate how 1 source of opioids differs substantially in the United States vs England. To reduce dental opioid prescribing in the United States, dentists could adopt measures similar to those used in England, including national guidelines for treating dental pain that emphasize prescribing opioids conservatively.
引用
收藏
页数:8
相关论文
共 25 条
[1]   History of The Joint Commission's Pain Standards Lessons for Today's Prescription Opioid Epidemic [J].
Baker, David W. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2017, 317 (11) :1117-1118
[2]   Opioid Prescribing After Surgical Extraction of Teeth in Medicaid Patients, 2000-2010 [J].
Baker, James A. ;
Avorn, Jerry ;
Levin, Raisa ;
Bateman, Brian T. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2016, 315 (15) :1653-1654
[3]  
Blinkhorn Anthony S, 2009, N S W Public Health Bull, V20, P52, DOI 10.1071/NB08067
[4]  
British National Formulary, 2016, BNF 72, P404
[5]  
Centers for Disease Control and Prevention National Center for Health Statistics, OR DENT HLTH
[6]   A randomised, five-parallel-group, placebo-controlled trial comparing the efficacy and tolerability of analgesic combinations including a novel single-tablet combination of ibuprofen/paracetamol for postoperative dental pain [J].
Daniels, Stephen E. ;
Goulder, Michael A. ;
Aspley, Sue ;
Reader, Sandie .
PAIN, 2011, 152 (03) :632-642
[7]  
Dowell Deborah, 2016, MMWR Recomm Rep, V65, P1, DOI [10.1001/jama.2016.1464, 10.15585/mmwr.rr6501e1]
[8]   CHRISTMAS 2015: FACE TIME Austin Powers bites back: a cross sectional comparison of US and English national oral health surveys [J].
Guarnizo-Herreno, Carol C. ;
Tsakos, Georgios ;
Sheiham, Aubrey ;
Marmot, Michael G. ;
Kawachi, Ichiro ;
Watt, Richard G. .
BMJ-BRITISH MEDICAL JOURNAL, 2015, 351
[9]   Opioid prescribing practices from 2010 through 2015 among dentists in the United States What do claims data tell us? [J].
Gupta, Niodita ;
Vujicic, Marko ;
Blatz, Andrew .
JOURNAL OF THE AMERICAN DENTAL ASSOCIATION, 2018, 149 (04) :237-+
[10]   Vital Signs: Changes in Opioid Prescribing in the United States, 2006-2015 [J].
Guy, Gery P., Jr. ;
Zhang, Kun ;
Bohm, Michele K. ;
Losby, Jan ;
Lewis, Brian ;
Young, Randall ;
Murphy, Louise B. ;
Dowell, Deborah .
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT, 2017, 66 (26) :697-704