ANALYSIS OF EFFECT OF PERIOPERATIVE BLOOD TRANSFUSION ON KIDNEY FUNCTIONS IN TOTAL KNEE ARTHROPLASTY

Introduction: A critical component of successful patient care in total knee arthroplasty (TKA) is a blood management strategy. TKA can result in substantial perioperative blood loss, rendering patients at increased risk of requiring allogenic blood transfusion. Aims and objectives: The main objective of the study is to analyze the effect of perioperative blood transfusion on kidney functions in total knee arthroplasty. Material and methods: This cross sectional study was conducted in Allama Iqbal Memorial Teaching Hospital, Gujranwala during August 2018 to January 2019. This study was basically done for the analysis of effect of blood transfusion on kidney functions in TKA. The data was collected from 100 patients of both genders. Age, gender, comorbidities like hypertension, diabetes mellitus, chronic obstructive lung disease, chronic renal disease and smoking habits as well as types of operations, anesthesia, preoperative and postoperative blood glucose levels, perioperative amounts of blood transfusion and postoperative morbidities and mortalities were recorded. Results: The data was collected from 100 patients of both genders. The mean age was 73.5 +/- 13.1 years. In terms of preoperative bloodwork, creatinine, aspartate aminotransferase (AS7) and alanine aminotransferase (ALT) levels were statistically similar (P> 0.05). However preoperative BUN level was statistically higher. When the patients were compared for blood parameters showing postoperative renal and other system functions, no statistical differences were detected (P > 0.05). Conclusion: It is concluded that postoperative complication rates increase with perioperative blood transfusion. In contrast to other surgical disciplines we could not prove that blood transfusion in orthopaedic surgery had adverse effects on postoperative renal functions.