Studies on synthesis of pyrimidine derivatives and their antimicrobial activity

被引：39

作者：

Mallikarjunaswamy, C. ^{[1
]}

Mallesha, L. ^{[2
]}

Bhadregowda, D. G. ^{[3
]}

Pinto, Othbert ^{[1
]}

机构：

[1] St Philomenas Coll, PG Dept Studies Chem, Mysore 15, Karnataka, India

[2] JSS Coll Arts Commerce & Sci, PG Dept Studies Chem, Ooty Rd, Mysore 25, Karnataka, India

[3] Univ Mysore, Dept Chem, Yuvarajas Coll, Mysore 5, Karnataka, India

来源：

ARABIAN JOURNAL OF CHEMISTRY | 2017年 / 10卷

关键词：

Pyrimidine derivatives; Sulfonyl chlorides; Antimicrobial activity;

D O I：

10.1016/j.arabjc.2012.10.008

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of novel 2-(5-bromo-2-chloro-pyrimidin-4-ylsulfanyl)-4-methoxy-phenylamine derivatives were synthesized by the reaction of 2-(5-bromo-2-chloro-pyrimidin-4-ylsulfanyl)-4-methoxy-phenylamine with various sulfonyl chlorides, and their in vitro antimicrobial activity was evaluated. The synthesized compounds were characterized by elemental analyses, FT-IR, H-1 NMR and LC-MS spectral studies. (C) 2012 Production and hosting by Elsevier B.V. on behalf of King Saud University.

引用

页码：S484 / S490

页数：7

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