The role of insulin pump therapy for type 2 diabetes mellitus

被引：24

作者：

Landau, Zohar ^{[1
,2
]}

Raz, Itamar ^{[3
]}

Wainstein, Julio ^{[2
]}

Bar-Dayan, Yosefa ^{[2
]}

Cahn, Avivit ^{[3
]}

机构：

[1] E Wolfson Med Ctr, Pediatr Endocrine & Diabet Unit, Holon, Israel

[2] Tel Aviv Univ, Sackler Sch Med, Tel Aviv, Israel

[3] Hadassah Univ Hosp, Dept Internal Med, Diabet Unit, Jerusalem, Israel

来源：

DIABETES-METABOLISM RESEARCH AND REVIEWS | 2017年 / 33卷 / 01期

关键词：

continuous subcutaneous insulin infusion; insulin pump; multiple daily injections; type; 2; diabetes; diabetes control; MULTIPLE DAILY INJECTIONS; BETA-CELL FUNCTION; TERM GLYCEMIC CONTROL; GLUCOSE VARIABILITY; PARALLEL-GROUP; INFUSION CSII; OLDER-ADULTS; IMPROVEMENT; HYPOGLYCEMIA; EFFICACY;

D O I：

10.1002/dmrr.2822

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Many patients with type 2 diabetes fail to achieve adequate glucose control despite escalation of treatment and combinations of multiple therapies including insulin. Patients with long-standing type 2 diabetes often suffer from the combination of severe insulin deficiency in addition to insulin resistance, thereby requiring high doses of insulin delivered in multiple injections to attain adequate glycemic control. Insulin-pump therapy was first introduced in the 1970s as an approach to mimic physiological insulin delivery and attain normal glucose in patients with type 1 diabetes. The recent years have seen an increase in the use of this technology for patients with type 2 diabetes. This article summarizes the clinical studies evaluating insulin pump use in patients with type 2 diabetes and discusses the benefits and shortcomings of pump therapy in this population. Copyright (C) 2016 John Wiley & Sons, Ltd.

引用

页数：13

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