Geldanamycin inhibits but does not reverse alpha-synuclein aggregation

被引:0
|
作者
McLean, PJ [1 ]
Klucken, J [1 ]
Shin, Y [1 ]
Hyman, BT [1 ]
机构
[1] Massachusetts Gen Hosp, Charlestown, MA USA
关键词
D O I
10.1016/S0197-4580(04)80617-1
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
引用
收藏
页码:S183 / S183
页数:1
相关论文
共 50 条
  • [41] Multiscale Investigation of Monomeric Alpha-Synuclein Structure and Aggregation
    Alvarado, Daisy
    Vazquez, Frank X.
    BIOPHYSICAL JOURNAL, 2019, 116 (03) : 496A - 496A
  • [42] Lysosomal degradation in Lewy bodies and alpha-synuclein aggregation
    Klucken, J.
    McLean, P. J.
    Winkler, J.
    Hyman, B. T.
    JOURNAL OF NEURAL TRANSMISSION, 2007, 114 (03) : X - XI
  • [43] Exploiting the Aggregation Properties of Alpha-Synuclein for Diagnostic Purposes
    Breen, David P.
    Kalia, Lorraine V.
    MOVEMENT DISORDERS, 2017, 32 (01) : 106 - 106
  • [44] Alpha-synuclein oligomerization and aggregation: A model will always be a model
    Outeiro, Tiago Fleming
    JOURNAL OF NEUROCHEMISTRY, 2021, 157 (04) : 889 - 890
  • [45] Understanding alpha-synuclein aggregation propensity in animals and humans
    Horgan, Natalie G.
    McCarty, Annie M.
    Hetak, Ashley A.
    Penticoff, Hailey B.
    Fortin, Jessica S.
    BIOCHEMISTRY AND BIOPHYSICS REPORTS, 2024, 39
  • [46] Alpha-synuclein aggregation in Gaucher patients and carriers with synucleinopathies
    Choi, Jae
    Stubblefield, Barbara
    Goker-Alpan, Ozlem
    Cookson, Mark
    Tayebi, Nahid
    Sidransky, Ellen
    MOLECULAR GENETICS AND METABOLISM, 2010, 99 (02) : S14 - S14
  • [47] Alpha-synuclein fragments trigger distinct aggregation pathways
    Chakroun, Tasnim
    Evsyukov, Valentin
    Nykaenen, Niko-Petteri
    Hoellerhage, Matthias
    Schmidt, Andreas
    Kamp, Frits
    Ruf, Viktoria C.
    Wurst, Wolfgang
    Roesler, Thomas W.
    Hoeglinger, Guenter U.
    CELL DEATH & DISEASE, 2020, 11 (02)
  • [48] Dexamethasone Inhibits Copper-Induced Alpha-Synuclein Aggregation by a Metallothionein-Dependent Mechanism
    McLeary, Fleur A.
    Rcom-H'cheo-Gauthier, Alexandre N.
    Kinder, Jessica
    Goulding, Michael
    Khoo, Tien K.
    Mellick, George D.
    Chung, Roger S.
    Pountney, Dean L.
    NEUROTOXICITY RESEARCH, 2018, 33 (02) : 229 - 238
  • [49] Epigallocatechin Gallate (EGCG) Inhibits Alpha-Synuclein Aggregation: A Potential Agent for Parkinson's Disease
    Xu, Yan
    Zhang, Yanyan
    Quan, Zhenzhen
    Wong, Winnie
    Guo, Jianping
    Zhang, Rongkai
    Yang, Qinghu
    Dai, Rongji
    McGeer, Patrick L.
    Qing, Hong
    NEUROCHEMICAL RESEARCH, 2016, 41 (10) : 2788 - 2796
  • [50] Alpha-Synuclein
    Schlossmacher, M.
    MOVEMENT DISORDERS, 2010, 25 : S581 - S581