CD81 as target for B cell lymphomas

被引：3
|
作者：
Kueppers, Ralf [1 ]
机构：
[1] Univ Duisburg Essen, Fac Med, Essen, Germany
来源：
JOURNAL OF EXPERIMENTAL MEDICINE | 2019年 / 216卷 / 07期
关键词：
D O I：
10.1084/jem.20190733
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In this issue of JEM, Vences-Catalan et al. (https://doi.org/10.1084/jem.20190186) demonstrate that a particular anti-CD81 antibody shows promising features as a novel immunotherapeutic tool to treat B cell lymphomas. Surprisingly, although CD81 is widely expressed, only minor side effects on other CD81(+) immune cells analyzed were observed.
引用
收藏
页码：1469 / 1470
页数：2
相关论文
共 50 条
  • [31] Distinct CD81 domains control CD19 maturation in B cells
    Shoham, T
    Rajapaksa, R
    Kuo, CC
    Haimovich, J
    Levy, S
    FASEB JOURNAL, 2005, 19 (04): : A881 - A881
  • [32] CD81 Protein Is Expressed in Normal Germinal Center B-Cells and in Subtypes of Human Non-Hodgkin Lymphomas
    Luo, R. F.
    Zhao, S.
    Tibshirani, R.
    Lossos, I. S.
    Advani, R.
    Gratzinger, D.
    Wong, A.
    Talrega, N.
    Levy, R.
    Levy, S.
    Natkunam, Y.
    LABORATORY INVESTIGATION, 2009, 89 : 275A - 275A
  • [33] CD81 Protein Is Expressed in Normal Germinal Center B-Cells and in Subtypes of Human Non-Hodgkin Lymphomas
    Luo, R. F.
    Zhao, S.
    Tibshirani, R.
    Lossos, I. S.
    Advani, R.
    Gratzinger, D.
    Wong, A.
    Talrega, N.
    Levy, R.
    Levy, S.
    Natkunam, Y.
    MODERN PATHOLOGY, 2009, 22 : 275A - 275A
  • [34] Differential expression of murine CD81 highlighted by new anti-mouse CD81 monoclonal antibodies
    Maecker, HT
    Todd, SC
    Kim, EC
    Levy, S
    HYBRIDOMA, 2000, 19 (01): : 15 - 22
  • [35] Characterization and verification of CD81 as a potential target in lung squamous cell carcinoma (vol 692, 149344, 2024)
    Ye, Xifu
    Deng, Junyuan
    Dong, Chengyuan
    Pan, Xue
    Lu, Yi
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 729
  • [36] Dissecting the role of putative CD81 binding regions of E2 in mediating HCV entry: Putative CD81 binding region 1 is not involved in CD81 binding
    Katharina B Rothwangl
    Balaji Manicassamy
    Susan L Uprichard
    Lijun Rong
    Virology Journal, 5
  • [37] The tetraspanin CD81 regulates the expression of CD19 during B cell development in a postendoplasmic reticulum compartment
    Shoham, T
    Rajapaksa, R
    Boucheix, C
    Rubinstein, E
    Poe, JC
    Tedder, TF
    Levy, S
    JOURNAL OF IMMUNOLOGY, 2003, 171 (08): : 4062 - 4072
  • [38] Dissecting the role of putative CD81 binding regions of E2 in mediating HCV entry: Putative CD81 binding region 1 is not involved in CD81 binding
    Rothwang, Katharina B.
    Manicassamy, Balaji
    Uprichard, Susan L.
    Rong, Lijun
    VIROLOGY JOURNAL, 2008, 5 (1)
  • [39] Expression of CD81 and CD117 in plasma cell myeloma and the relationship to prognosis
    Chen, F.
    Wang, X.
    Fu, S.
    Zhang, J.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 1581 - 1581
  • [40] Expression of CD81 and CD117 in plasma cell myeloma and the relationship to prognosis
    Chen, Fang
    Hu, Yanping
    Wang, Xiaohui
    Fu, Shuang
    Liu, Zhuogang
    Zhang, Jihong
    CANCER MEDICINE, 2018, 7 (12): : 5920 - 5927
12345