CD81 as target for B cell lymphomas

被引:3
|
作者
Kueppers, Ralf [1 ]
机构
[1] Univ Duisburg Essen, Fac Med, Essen, Germany
来源
JOURNAL OF EXPERIMENTAL MEDICINE | 2019年 / 216卷 / 07期
关键词
D O I
10.1084/jem.20190733
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In this issue of JEM, Vences-Catalan et al. (https://doi.org/10.1084/jem.20190186) demonstrate that a particular anti-CD81 antibody shows promising features as a novel immunotherapeutic tool to treat B cell lymphomas. Surprisingly, although CD81 is widely expressed, only minor side effects on other CD81(+) immune cells analyzed were observed.
引用
收藏
页码:1469 / 1470
页数:2
相关论文
共 50 条
  • [1] Treating B Cell Lymphomas with Anti CD81 Antibodies
    Vences-Catalan, Felipe
    Kuo, Chiung-Chi
    Rajapaksa, Ranjani
    Duault, Caroline
    Levy, Ronald
    Levy, Shoshana
    BLOOD, 2016, 128 (22)
  • [2] CD81 is a novel immunotherapeutic target for B cell lymphoma
    Vences-Catalan, Felipe
    Kuo, Chiung-Chi
    Rajapaksa, Ranjani
    Duault, Caroline
    Andor, Noemi
    Czerwinski, Debra K.
    Levy, Ronald
    Levy, Shoshana
    JOURNAL OF EXPERIMENTAL MEDICINE, 2019, 216 (07): : 1497 - 1508
  • [3] CD81: A new target for therapy of B cell lymphoma
    Vences-Catalan, Felipe
    Kuo, Chiung-Chi
    Rajapaksa, Ranjani
    Levy, Ronald
    Levy, Shoshana
    CANCER IMMUNOLOGY RESEARCH, 2016, 4 (11)
  • [4] CD81 as a tumor target
    Vences-Catalan, Felipe
    Duault, Caroline
    Kuo, Chiung-Chi
    Rajapaksa, Ranjani
    Levy, Ronald
    Levy, Shoshana
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2017, 45 : 531 - 535
  • [5] Enhanced B cell activation in the absence of CD81
    Sanyal, Mrinmoy
    Fernandez, Rosemary
    Levy, Shoshana
    INTERNATIONAL IMMUNOLOGY, 2009, 21 (11) : 1225 - 1237
  • [6] Critical role for CD81 in B cell activation
    Li, Zhaoyang
    Xue, Liquan
    Shin, Dong-Mi
    Qi, Chen-Feng
    Zhang, Quangeng
    Xu, Wu
    Morris, Stephan W.
    Morse, Herbert
    Wang, Hongsheng
    BLOOD, 2007, 110 (11) : 404A - 404A
  • [7] B cell signaling is regulated by induced palmitoylation of CD81
    Cherukuri, A
    Carter, RH
    Brooks, S
    Bornmann, W
    Finn, R
    Dowd, CS
    Pierce, SK
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (30) : 31973 - 31982
  • [8] CD81: a novel lymphoma therapeutic target
    Catalan, Felipe Vences
    Kuo, Chiung-chi
    Rajapaksa, Ranjani
    Duault, Caroline
    Levy, Ronald
    Levy, Shoshana
    JOURNAL OF IMMUNOLOGY, 2017, 198 (01):
  • [9] CD81 as a target to inhibit transendothelial migration of monocytes
    Dijkstra, S
    Kooij, G
    van der Pol, SMA
    Geisert, EE
    de Vries, HE
    van Noort, JM
    JOURNAL OF NEUROIMMUNOLOGY, 2004, 154 (1-2) : 67 - 67
  • [10] Characterization and verification of CD81 as a potential target in lung squamous cell carcinoma
    Ye, Xifu
    Deng, Junyuan
    Dong, Chengyuan
    Pan, Xue
    Lu, Yi
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 692