Increased serum levels of the interferon-γ-inducing cytokine interleukin-18 in myasthenia gravis

被引：31
|
作者：
Jander, S [1 ]
Stoll, G [1 ]
机构：
[1] Univ Dusseldorf, Dept Neurol, D-40225 Dusseldorf, Germany
来源：
NEUROLOGY | 2002年 / 59卷 / 02期
关键词：
D O I：
10.1212/WNL.59.2.287
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
In this study, the authors show that MG as an autoantibody-mediated disorder of neuromuscular transmission is associated with elevated serum levels of the interferon-gamma-inducing cytokine interleukin (IL)-18. IL-18 levels were higher in generalized than in ocular myasthenia and tended to decrease on clinical improvement. These findings suggest an unexpected role of IL-18 in B-cell-mediated autoimmune disease.
引用
收藏
页码：287 / 289
页数：3
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