Increased serum levels of the interferon-γ-inducing cytokine interleukin-18 in myasthenia gravis

被引：32

作者：

Jander, S ^{[1
]}

Stoll, G ^{[1
]}

机构：

[1] Univ Dusseldorf, Dept Neurol, D-40225 Dusseldorf, Germany

来源：

NEUROLOGY | 2002年 / 59卷 / 02期

关键词：

D O I：

10.1212/WNL.59.2.287

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In this study, the authors show that MG as an autoantibody-mediated disorder of neuromuscular transmission is associated with elevated serum levels of the interferon-gamma-inducing cytokine interleukin (IL)-18. IL-18 levels were higher in generalized than in ocular myasthenia and tended to decrease on clinical improvement. These findings suggest an unexpected role of IL-18 in B-cell-mediated autoimmune disease.

引用

页码：287 / 289

页数：3

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