Sleep symptoms and their clinical correlates in Machado-Joseph disease

被引：32

作者：

D'Abreu, A. ^{[2
]}

Franca, M., Jr. ^{[3
]}

Conz, L. ^{[2
]}

Friedman, J. H. ^{[4
,5
]}

Nucci, A. M. ^{[3
]}

Cendes, F. ^{[2
,3
]}

Lopes-Cendes, I. ^{[1
]}

机构：

[1] Univ Campinas UNICAMP, Fac Med Sci, Dept Med Genet, BR-13084971 Campinas, SP, Brazil

[2] Univ Campinas UNICAMP, Neuroimaging Lab, BR-13084971 Campinas, SP, Brazil

[3] Univ Campinas UNICAMP, Fac Med Sci, Dept Neurol, BR-13084971 Campinas, SP, Brazil

[4] Brown Univ, Warren Alpert Sch Med, NeuroHlth Parkinsons Dis & Movement Disorders Ctr, Providence, RI 02912 USA

[5] Brown Univ, Warren Alpert Sch Med, Dept Clin Neurosci, Providence, RI 02912 USA

来源：

ACTA NEUROLOGICA SCANDINAVICA | 2009年 / 119卷 / 04期

关键词：

ataxia; Machado-Joseph disease; sleep; restless leg syndrome; REM sleep behavior disorder; RESTLESS LEGS SYNDROME; BEHAVIOR DISORDER; ATAXIA; APNEA;

D O I：

10.1111/j.1600-0404.2008.01092.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To evaluate the presence of sleep symptoms in Machado-Joseph disease/spinocerebellar ataxia type 3 (MJD/SCA3). We used a sleep questionnaire and the Epworth Sleepiness Scale to compare 53 patients with MJD/SCA3 and 106 controls. Patients with MJD/SCA3 reported more symptoms of insomnia, restless leg syndrome and REM sleep behavior disorder as well as nocturnal cramps, snoring and nocturnal apnea. Insomnia was the most frequently reported sleep-related complaint in the MJD/SCA3 group. Our results indicate that sleep disorders are common in patients with MJD/SCA3 and probably have a multifactorial etiology, with components of a primary sleep disorder in addition to sleep-disrupting symptoms such as nocturia and cramps.

引用

页码：277 / 280

页数：4

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