Follicular necrotic keratinocytes - a helpful clue to the diagnosis of measles

被引:8
作者
Tirado, Mariantonieta [1 ]
Adamzik, Karoline [2 ]
Boeer-Auer, Almut [3 ]
机构
[1] Marien Hosp, Dept Pathol, Dermatol Diagnost, Hamburg, Germany
[2] Univ Kiel, Dept Dermatol, Kiel, Germany
[3] Dermatol Hamburg, Dept Dermatol, Hamburg, Germany
关键词
dermatopathology; exanthema; follicular necrotic keratinocytes; measles; syncytial-type multinucleated epithelial cell; GIANT-CELL; RASH; VIRUS; LIGHT;
D O I
10.1111/cup.12529
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
A skin specimen taken from the exanthem of a 22-year-old man with measles infection was examined by light microscopy. The most characteristic changes were foci of multiple necrotic keratinocytes, partially confluent and partially isolated, strictly within follicles and sebaceous glands. Serial sections revealed occasional necrotic and none-necrotic syncytial-type multinucleated epithelial cells in some infundibula. Neither nuclear nor cytoplasmic viral inclusions were present.
引用
收藏
页码:632 / 638
页数:7
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