Diffusion-weighted MR imaging using FASE sequence for 3T MR system: Preliminary comparison of capability for N-stage assessment by means of diffusion-weighted MR imaging using EPI sequence, STIR FASE imaging and FDG PET/CT for non-small cell lung cancer patients

被引：24
作者：
Ohno, Yoshiharu [1 ,2 ]
Koyama, Hisanobu [3 ]
Yoshikawa, Takeshi [1 ,2 ]
Takenaka, Daisuke [4 ]
Kassai, Yoshimori [5 ]
Yui, Masao [5 ]
Matsumoto, Sumiaki [1 ,2 ]
Sugimura, Kazuro [3 ]
机构：
[1] Kobe Univ, Grad Sch Med, Adv Biomed Imaging Res Ctr, Kobe, Hyogo 6500017, Japan
[2] Kobe Univ, Grad Sch Med, Dept Radiol, Div Funct & Diagnost Imaging Res, Kobe, Hyogo 6500017, Japan
[3] Kobe Univ, Grad Sch Med, Dept Radiol, Div Radiol, Kobe, Hyogo 6500017, Japan
[4] Hyogo Canc Ctr, Dept Radiol, Akashi, Hyogo, Japan
[5] Toshiba Med Syst Corp, Otawara, Tochigi, Japan
来源：
EUROPEAN JOURNAL OF RADIOLOGY | 2015年 / 84卷 / 11期
关键词：
Lung; MR imaging; PET/CT; Diffusion; Lung cancer; Staging; TURBO SPIN-ECHO; POSITRON-EMISSION-TOMOGRAPHY; QUALITATIVE ASSESSMENT; LYMPH-NODES; BODY; METASTASES; PROSTATE;
D O I：
10.1016/j.ejrad.2015.07.019
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Purpose: To prospectively compare the diagnostic capability of diffusion-weighted MR imaging obtained with fast advantage spin-echo sequence (FASE-DWI) and echo planar imaging sequence (EPI-DWI), short inversion time inversion recovery fast advanced spin-echo (STIR FASE) imaging and FDG PET/CT for N-stage assessment of non-small cell carcinoma (NSCLC) patients. Materials and methods: 95 consecutive operable NSCLC patients underwent STIR FASE imaging, FASE-DWI and EPI-DWI with a 3T system, integrated PET/CT, surgical treatment and pathological and follow-up examinations. Probability of lymph node metastasis was visually assessed using a 5-point visual scoring system. ROC analyses were used to compare diagnostic capability of all methods, while their diagnostic performance was also compared by means of McNemar's test on a per node basis. Finally, McNemar's test was also used for statistical comparison of accuracy of N-stage assessment. Results: Areas under the curve (Azs) for STIR FASE imaging (Az = 0.95) and FASE-DWI (Az = 0.92) were significantly larger than those for EPI-DWI (Az = 0.78; p <0.0001 for STIR FSE imaging and FASE-DWI) and PET/CT (Az = 0.85; p = 0.0001 for STIR FSE imaging, p = 0.03 for FASE-DWI) on a per node basis analysis. Accuracy of N-stage assessment using STIR FASE imaging (84.2% [80195]) and FASE-DWI (83.2% [79195]) was significantly higher than that using EPI-DWI (76.8% [73195]; p = 0.02 for STIR FASE imaging, p = 0.03 for FASE-DWI) and PET/CT (73.7% [70195]; p = 0.002 for STIR FSE imaging, p = 0.004 for FASE-DWI). Conclusion: Qualitative N-stage assessments of NSCLC patients obtained with FASE-DWI as well as STIR FASE imaging are more sensitive and/or accurate than those obtained with EPI-DWI and FDG PET/CT. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
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收藏
页码：2321 / 2331
页数：11
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