Low hazard small-scale synthesis and chemical analysis of high purity nitroglycerine (NG)

被引：8

作者：

Contini, Alessandro E. ^{[1
]}

Flood, Nathan ^{[1
]}

McAteer, Daniel ^{[1
]}

Mai, Nathalie ^{[1
]}

Akhavan, Jacqueline ^{[1
]}

机构：

[1] Cranfield Univ, Ctr Def Chem, Def Acad United Kingdom, Shrivenham SN6 8LA, Wilts, England

来源：

RSC ADVANCES | 2015年 / 5卷 / 106期

关键词：

EXPLOSIVES;

D O I：

10.1039/c5ra17951c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A previously reported two-phase (99.5% fuming nitric acid/dichloromethane) batch method to prepare high purity 1,2,3-propanetriyl trinitrate (nitroglycerine, NG) was evaluated, simplified and adapted specifically for low hazard small-scale synthesis. The purity of the product, as determined by NMR spectroscopy, HPLC and IR spectroscopic analysis was found to be greater than 99%. The quick synthetic method is highly recommended when small amounts of highly pure NG are required for analytical and related purposes in the absence of a microreactor.

引用

页码：87228 / 87232

页数：5

共 30 条

[1]

Bowden F.P., 1985, INITIATION GROWTH EX

[2]

Braune S., 2011, US Pat., Patent No. [US 12/808,829, 12808829]

[3]

Camera E., 1982, Propellants Explos Pyrotech, V7, P66, DOI [10.1002/prep.19820070303, DOI 10.1002/PREP.19820070303]

[4] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS OF NITROGLYCERIN OINTMENT [J].

GELBER, L .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1980, 69 (09) :1084-1086

[5]

Gordon A. S., 1938, US Pat., Patent No. [US 2140897 A, 2140897]

[6] Ambient mass spectrometry: advances and applications in forensics [J].

Green, F. M. ;

Salter, T. L. ;

Stokes, P. ;

Gilmore, I. S. ;

O'Connor, G. .

SURFACE AND INTERFACE ANALYSIS, 2010, 42 (05) :347-357

[7]

Grigor'eva V. Y., 2004, PHARM CHEM J, V38, P562

[8] Microwave-assisted hydrolysis of nitroglycerin (NG) under mild alkaline conditions: New insight into the degradation pathway [J].

Halasz, Annamaria ;

Thiboutot, Sonia ;

Ampleman, Guy ;

Hawari, Jalal .

CHEMOSPHERE, 2010, 79 (02) :228-232

[9]

Heng S.Y., 1991, Propellants, Explosives,Pyrotechnics, V16, P31

[10] Lab on a chip: A little goes a long way [J].

Hogan, Jenny .

NATURE, 2006, 442 (7101) :351-352

← 1 2 3 →