3-D maps and coupling numbers for protein sequences

被引：41

作者：

Li, Chun ^{[1
]}

Yu, Xiaoqing ^{[1
]}

Yang, Liu ^{[1
]}

Zheng, Xiaoqi ^{[2
]}

Wang, Zhifu ^{[1
]}

机构：

[1] Bohai Univ, Dept Math, Jinzhou 121013, Peoples R China

[2] Dalian Univ Technol, Dept Appl Math, Dalian 116024, Peoples R China

来源：

PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS | 2009年 / 388卷 / 09期

基金：

中国国家自然科学基金;

关键词：

Protein; Graphical representation; Coupling numbers; Similarity; 2-D GRAPHICAL REPRESENTATION; CHAOS-GAME REPRESENTATION; DNA PRIMARY SEQUENCES; ARC REPRESSOR MUTANTS; NUMERICAL CHARACTERIZATION; MOLECULAR DESCRIPTORS; QSAR; PREDICTION; RECOGNITION; DEGENERACY;

D O I：

10.1016/j.physa.2009.01.017

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Based on a five-letter model of the 20 amino acids, we propose a new 3-D graphical representation of protein sequence. Then we derive from the graphical representation. numerical indices called 3-D coupling numbers, to characterize protein sequences. The examination of the similarities/dissimilarities among the beta-globin proteins of 15 species illustrates the utility of the approach. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：1967 / 1972

页数：6

共 42 条

[21] A rapid method for quantitative prediction of high affinity CTL epitopes: QSAR studies on peptides having affinity with the class I MHC molecular HLA-A*0201 [J].