Central Centrifugal Cicatricial Alopecia What Has Been Achieved, Current Clues for Future Research

被引：42
|
作者：
Ogunleye, Temitayo A. [1 ]
McMichael, Amy [2 ]
Olsen, Elise A. [3 ]
机构：
[1] Univ Penn, Perelman Ctr Adv Med, Dept Dermatol, Philadelphia, PA 19104 USA
[2] Wake Forest Baptist Hlth, Dept Dermatol, Winston Salem, NC 27104 USA
[3] Duke Univ, Med Ctr, Hair Disorders Res & Treatment Ctr, Dept Dermatol, Durham, NC 27710 USA
来源：
DERMATOLOGIC CLINICS | 2014年 / 32卷 / 02期
关键词：
Central centrifugal cicatricial alopecia; Hot comb alopecia; Scarring alopecia; Follicular degeneration syndrome; FOLLICULAR DEGENERATION SYNDROME; HOT COMB ALOPECIA; SCALP DISEASE; ETHNIC HAIR; SKIN; PREVALENCE; LIGHT; WOMEN;
D O I：
10.1016/j.det.2013.12.005
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Central centrifugal cicatricial alopecia is an inflammatory type of central scalp hair loss seen primarily in women of African descent. The prevalence is unknown, but may vary from 2.7% to 5.7% and increases with age. This review outlines the history and current beliefs and identifies clues for future research for this enigmatic condition. Despite that the cause of central centrifugal cicatricial alopecia is unknown, research is ongoing. The role of cytokeratins, androgens, genetics, and various possible sources of chronic inflammation in disease pathogenesis remain to be elucidated.
引用
收藏
页码：173 / +
页数：10
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