Fetal QRS detection and heart rate estimation: a wavelet-based approach

被引:28
作者
Almeida, Rute [1 ,3 ,4 ]
Goncalves, Hernani [5 ]
Bernardes, Joao [5 ,6 ,7 ,8 ]
Rocha, Ana Paula [1 ,2 ]
机构
[1] Univ Porto, Fac Ciencias, Ctr Matemat, Rua Campo Alegre 687, P-4169007 Oporto, Portugal
[2] Univ Porto, Fac Ciencias, Dept Matemat, P-4169007 Oporto, Portugal
[3] CIBER BBN, Biomed Res Networking Ctr Bioengn Biomat & Nanome, Zaragoza, Aragon, Spain
[4] Univ Zaragoza, IIS Aragon, Aragon Inst Engn Res I3A, BSICoS Grp, Zaragoza, Aragon, Spain
[5] Univ Porto, Fac Med, Ctr Res Hlth Technol & Informat Syst CINTESIS, P-4100 Oporto, Portugal
[6] Univ Porto, Fac Med, Dept Obstet & Gynecol, Oporto, Portugal
[7] Sao Joao Hosp, Dept Obstet & Gynecol, Oporto, Portugal
[8] INEB Inst Biomed Engn, Oporto, Portugal
关键词
wavelet transform; abdominal fetal electrocardiogram; QRS detection; fetal heart rate; FETUSES;
D O I
10.1088/0967-3334/35/8/1723
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Fetal heart rate monitoring is used for pregnancy surveillance in obstetric units all over the world but in spite of recent advances in analysis methods, there are still inherent technical limitations that bound its contribution to the improvement of perinatal indicators. In this work, a previously published wavelet transform based QRS detector, validated over standard electrocardiogram (ECG) databases, is adapted to fetal QRS detection over abdominal fetal ECG. Maternal ECG waves were first located using the original detector and afterwards a version with parameters adapted for fetal physiology was applied to detect fetal QRS, excluding signal singularities associated with maternal heartbeats. Single lead (SL) based marks were combined in a single annotator with post processing rules (SLR) from which fetal RR and fetal heart rate (FHR) measures can be computed. Data from PhysioNet with reference fetal QRS locations was considered for validation, with SLR outperforming SL including ICA based detections. The error in estimated FHR using SLR was lower than 20 bpm for more than 80% of the processed files. The median error in 1 min based FHR estimation was 0.13 bpm, with a correlation between reference and estimated FHR of 0.48, which increased to 0.73 when considering only records for which estimated FHR > 110 bpm. This allows us to conclude that the proposed methodology is able to provide a clinically useful estimation of the FHR.
引用
收藏
页码:1723 / 1735
页数:13
相关论文
共 21 条
[1]  
Almeida R, 2013, COMPUT CARDIOL CONF, V40, P289
[2]  
[Anonymous], 1995, Int J Gynaecol Obstet, V49, P213
[3]  
[Anonymous], 2005, OBSTET GYNECOLOGY, V106, P1453
[4]  
Bolea J, 2009, 2009 9TH INTERNATIONAL CONFERENCE ON INFORMATION TECHNOLOGY AND APPLICATIONS IN BIOMEDICINE, P254
[5]   Efficient wavelet-based ECG processing for single-lead FHR extraction [J].
Castillo, E. ;
Morales, D. P. ;
Botella, G. ;
Garcia, A. ;
Parrilla, L. ;
Palma, A. J. .
DIGITAL SIGNAL PROCESSING, 2013, 23 (06) :1897-1909
[6]   Cardiac time intervals of normal fetuses using noninvasive fetal electrocardiography [J].
Chia, EL ;
Ho, TF ;
Rauff, M ;
Yip, WCL .
PRENATAL DIAGNOSIS, 2005, 25 (07) :546-552
[7]   Non-invasive fetal ECG analysis [J].
Clifford, Gari D. ;
Silva, Ikaro ;
Behar, Joachim ;
Moody, George B. .
PHYSIOLOGICAL MEASUREMENT, 2014, 35 (08) :1521-1536
[8]   Revisiting QRS Detection Methodologies for Portable, Wearable, Battery-Operated, and Wireless ECG Systems [J].
Elgendi, Mohamed ;
Eskofier, Bjoern ;
Dokos, Socrates ;
Abbott, Derek .
PLOS ONE, 2014, 9 (01)
[9]   PhysioBank, PhysioToolkit, and PhysioNet - Components of a new research resource for complex physiologic signals [J].
Goldberger, AL ;
Amaral, LAN ;
Glass, L ;
Hausdorff, JM ;
Ivanov, PC ;
Mark, RG ;
Mietus, JE ;
Moody, GB ;
Peng, CK ;
Stanley, HE .
CIRCULATION, 2000, 101 (23) :E215-E220
[10]   Linear and nonlinear fetal heart rate analysis of normal and acidemic fetuses in the minutes preceding delivery [J].
Goncalves, Hernani ;
Rocha, Ana Paula ;
Ayres-de-Campos, Diogo ;
Bernardes, Joao .
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 2006, 44 (10) :847-855