Degenerative Liver Disease in Young Beagles with Hereditary Cobalamin Malabsorption Because of a Mutation in the Cubilin Gene

被引：12
作者：
Kook, P. H. [1 ]
Droegemueller, M. [2 ]
Leeb, T. [2 ]
Howard, J. [3 ]
Ruetten, M. [4 ]
机构：
[1] Univ Zurich, Clin Small Anim Internal Med, Vetsuisse Fac, CH-8057 Zurich, Switzerland
[2] Univ Bern, Inst Genet, Vetsuisse Fac, Bern, Switzerland
[3] Univ Bern, Dept Clin Vet Med, Dept Clin Vet Med, Bern, Switzerland
[4] Univ Zurich, Inst Vet Pathol, Vetsuisse Fac, CH-8057 Zurich, Switzerland
来源：
JOURNAL OF VETERINARY INTERNAL MEDICINE | 2014年 / 28卷 / 02期
关键词：
Neutropenia; Vitamin B12; Hepatopathy; Ascites; BORDER COLLIES; DEFICIENCY; EXPRESSION; ALPHA;
D O I：
10.1111/jvim.12295
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
[No abstract available]
引用
收藏
页码：666 / 671
页数：6
相关论文
共 23 条
  • [1] Hyperammonaemic encephalopathy secondary to selective cobalamin deficiency in a juvenile Border collie
    Battersby, IA
    Giger, U
    Hall, EJ
    [J]. JOURNAL OF SMALL ANIMAL PRACTICE, 2005, 46 (07) : 339 - 344
  • [2] WHITE LIVER-DISEASE IN GOATS
    BLACK, H
    HUTTON, JB
    SUTHERLAND, RJ
    JAMES, MP
    [J]. NEW ZEALAND VETERINARY JOURNAL, 1988, 36 (01) : 15 - 17
  • [3] A frameshift mutation in the cubilin gene (CUBN) in Beagles with Imerslund-Grasbeck syndrome (selective cobalamin malabsorption)
    Droegemueller, Michaela
    Jagannathan, Vidhya
    Howard, Judith
    Bruggmann, Remy
    Droegemueller, Cord
    Ruetten, Maja
    Leeb, Tosso
    Kook, Peter H.
    [J]. ANIMAL GENETICS, 2014, 45 (01) : 148 - 150
  • [4] Persistent cobalamin deficiency causing failure to thrive in a juvenile beagle
    Fordyce, HH
    Callan, MB
    Giger, U
    [J]. JOURNAL OF SMALL ANIMAL PRACTICE, 2000, 41 (09) : 407 - 410
  • [5] INHERITED SELECTIVE INTESTINAL COBALAMIN MALABSORPTION AND COBALAMIN DEFICIENCY IN DOGS
    FYFE, JC
    GIGER, U
    HALL, CA
    JEZYK, PF
    KLUMPP, SA
    LEVINE, JS
    PATTERSON, DF
    [J]. PEDIATRIC RESEARCH, 1991, 29 (01) : 24 - 31
  • [6] Imerslund-Grasbeck syndrome (selective vitamin B12 malabsorption with proteinuria)
    Grasbeck, Ralph
    [J]. ORPHANET JOURNAL OF RARE DISEASES, 2006, 1 (1)
  • [7] Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B12) absorption in vivo
    He, QC
    Madsen, M
    Kilkenney, A
    Gregory, B
    Christensen, EI
    Vorum, H
    Hojrup, P
    Schäffer, AA
    Kirkness, EF
    Tanner, SM
    de la Chapelle, A
    Giger, U
    Moestrup, SK
    Fyfe, JC
    [J]. BLOOD, 2005, 106 (04) : 1447 - 1453
  • [8] Role of TNF-α in ethanol-induced hyperhomocysteinemia and murine alcoholic liver injury
    Ji, C
    Deng, QG
    Kaplowitz, N
    [J]. HEPATOLOGY, 2004, 40 (02) : 442 - 451
  • [9] KENNEDY DG, 1994, INT J VITAM NUTR RES, V64, P270
  • [10] Histopathologic and ultrastructural alterations of white liver disease in sheep experimentally depleted of cobalt
    Kennedy, S
    McConnell, S
    Anderson, H
    Kennedy, DG
    Young, PB
    Blanchflower, WJ
    [J]. VETERINARY PATHOLOGY, 1997, 34 (06) : 575 - 584
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