Mechanical solutions to salvage failed distraction osteogenesis in large bone defect management

被引:21
作者
Borzunov, Dmitry Y. [1 ]
Shastov, Alexander L. [1 ]
机构
[1] Russian Ilizarov Sci Ctr Restorat Traumatol & Ort, 6 M Ulianova St, Kurgan 640014, Russia
关键词
Bone defect; Bone fragment; Ilizarov transport; Distraction osteogenesis; Bone callus; Failed regeneration; Compression; CALLUS; RECONSTRUCTION; CLASSIFICATION; EXPERIENCE; TRANSPORT; PATTERNS;
D O I
10.1007/s00264-018-4032-6
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
IntroductionIlizarov bone transport for large bone defect is challenging and may end in distraction osteogenesis failure.Material and methodsTen forearm and seven tibial defect cases with failed regeneration due to ischaemia during bone transport were studied retrospectively. Mean forearm and tibial defects were 5.50.8 and 7.61cm respectively, or 22.3 +/- 3.6 and 20 +/- 2.3% as compared with healthy segments. Most patients had numerous previous operations (2.6 +/- 0.5 and 3.4 +/- 0.8 per patient, respectively), extensive scars locally and post-traumatic neuropathy. There were seven infected defects. Mechanical solutions used were (1) additional osteotomy and transport of the fragment to compact the ischaemic regenerate (10 forearms, 4 tibias) and (2) compaction of the connective tissue layer in the tibial regenerate with either two 5-mm steps (two cases) or gradually (one case).Results p id=Par3 Bone integrity was restored in all the cases. Complete compensation of the defects was achieved in 12 patients with the first technique. Two patients with 8-cm ulna defects remained with residual discrepancy. In the forearm, mean compaction was 1.7 +/- 0.4cm. It took 25.7 +/- 5.4days followed by an average fixation period of 107.1 +/- 11.8days. In the tibia, mean longitudinal compaction by distraction measured 1.7 +/- 0.8cm. The second technique ended up with an acceptable shortening of 1cm in two cases. Four centimeters were compressed in the third case gradually.Conclusionp id=ParThe technical solutions used for mechanical effects on the ischaemic distraction regenerate resulted in its rescue and bone union in all the cases.
引用
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页码:1051 / 1059
页数:9
相关论文
共 26 条
  • [1] The effect of altering the mechanical loading environment on the expression of bone regenerating molecules in cases of distraction osteogenesis
    Alzahrani, Mohammad M.
    Anam, Emad A.
    Makhdom, Asim M.
    Villemure, Isabelle
    Hamdy, Reggie Charles
    [J]. FRONTIERS IN ENDOCRINOLOGY, 2014, 5
  • [2] ARONSON J, 1994, CLIN ORTHOP RELAT R, P124
  • [3] Aronson J., 2007, LIMB LENGTHENING REC, P19
  • [4] Our experience in the management of segmental bone defects caused by gunshots
    Azzam, Wael
    Atef, Ashraf
    [J]. INTERNATIONAL ORTHOPAEDICS, 2016, 40 (02) : 233 - 238
  • [5] Long bone reconstruction using multilevel lengthening of bone defect fragments
    Borzunov, Dmitry Y.
    [J]. INTERNATIONAL ORTHOPAEDICS, 2012, 36 (08) : 1695 - 1700
  • [6] Angiogenesis and mineralization during distraction osteogenesis
    Choi, IH
    Chung, CY
    Cho, TJ
    Yoo, WJ
    [J]. JOURNAL OF KOREAN MEDICAL SCIENCE, 2002, 17 (04) : 435 - 447
  • [7] Management of posttraumatic segmental bone defects
    DeCoster, TA
    Gehlert, R
    Mikola, EA
    Pirela-Cruz, MA
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS, 2004, 12 (01) : 28 - 38
  • [8] El-Alfy B, 2009, ACTA ORTHOP BELG, V75, P368
  • [9] Methods to shorten the duration of an external fixator in the management of tibial infections
    Emara, Khaled M.
    Abd Al Ghafar, Khaled
    Al Kersh, Mohamed Ahmed
    [J]. WORLD JOURNAL OF ORTHOPEDICS, 2011, 2 (09): : 85 - 92
  • [10] Bone Lengthening in the Pediatric Upper Extremity
    Farr, Sebastian
    Mindler, Gabriel
    Ganger, Rudolf
    Girsch, Werner
    [J]. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2016, 98 (17) : 1490 - 1503