Formation Mechanism Analysis of Shear-Induced Microgel Filaments during Microfluidic Gelation

被引：1

作者：

Fukushima, Shuhei ^{[1
]}

Takayama, Yuriko ^{[1
]}

Nasuno, Eri ^{[1
]}

Yanagida, Yasuko ^{[2
]}

Kato, Norihiro ^{[1
]}

机构：

[1] Utsunomiya Univ, Sch Engn, Dept Fundamental Engn, 7-1-2 Yoto, Utsunomiya, Tochigi 3218585, Japan

[2] Tokyo Inst Technol, Inst Innovat Res, Lab Future Interdisciplinary Res Sci & Technol, Midori Ku, 4259 Nagatsuda Cho, Yokohama, Kanagawa 2268503, Japan

来源：

MACROMOLECULAR MATERIALS AND ENGINEERING | 2021年 / 306卷 / 02期

关键词：

fibers; hydrogels; microgels; phase separation; polysaccharides; GEL FIBERS; CONFORMATION; BIOMATERIALS; FABRICATION; NANOFIBERS;

D O I：

10.1002/mame.202000586

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Dynamic microfluidic gelation enables the fabrication of bundle-structured multiple parallel microgel filaments from an aqueous two-phase system. The formation mechanism of shear-induced filaments from an alginate (Alg)/polyvinyl alcohol (PVA) blend is studied using red-colored PVA and a titanium alkoxide PVA crosslinker. Bundle-structured Alg microgel filaments are formed through contact with a Ca2+ crosslinker. In this process, the PVA acts as a sacrificial polymer to maintain the Alg gel filaments because approximately 90% of the red-colored PVA is released from the Ca2+-crosslinked Alg gel filaments into the wash water. In addition, the fabrication of PVA gel filaments shows that the sacrificial PVA is also transformed into fibrillar domains under shear. However, the filament structure cannot be formed from a single-phase PVA/Alg solution. These results clearly show that the bundle-structured gel filaments are maintained by preventing the fusion of filaments during gelation based on the tendency of the non-crosslinked filaments to cause splitting of the gelled filaments.

引用

页数：5

共 23 条

[1] Molecular basis of Ca2+-induced gelation in alginates and pectins:: The egg-box model revisited [J].