Triple Negative Breast Cancer

被引:36
|
作者
Cetin, Idil [1 ]
Topcul, Mehmet [2 ]
机构
[1] Istanbul Univ, Fac Sci, Dept Radiobiol, Istanbul, Turkey
[2] Istanbul Univ, Fac Sci, Dept Biol, Istanbul, Turkey
关键词
Triple negative breast cancer; poor prognosis; targeted therapy; ENDOTHELIAL GROWTH-FACTOR; FACTOR RECEPTOR; MOLECULAR SUBTYPES; RISK-FACTORS; STEM-CELLS; PROGNOSTIC VALUE; BASAL; CHEMOTHERAPY; CARCINOMA; SURVIVAL;
D O I
10.7314/APJCP.2014.15.6.2427
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Triple-negative breast cancers (TNBC), characterized by absence of the estrogen receptor (ER) and progesterone receptor (PR) and lack of overexpression of human epidermal growth factor receptor 2 (HER2), have a poor prognosis. To overcome therapy limitations of TNBC, various new approaches are needed. This mini-review focuses on discovery of new targets and drugs which might offer new hope for TNBC patients.
引用
收藏
页码:2427 / 2431
页数:5
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