Incontinence after radical prostatectomy: Anything new in its management?

被引:19
作者
Caremel, Romain [1 ]
Corcos, Jacques [1 ]
机构
[1] McGill Univ, Jewish Gen Hosp, Dept Urol, Montreal, PQ H3T 1E2, Canada
来源
CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL | 2014年 / 8卷 / 5-6期
关键词
STRESS URINARY-INCONTINENCE; QUALITY-OF-LIFE; SURGICAL-TREATMENT; CONTINENCE; IMPLANTATION; DULOXETINE; SPHINCTER; PRESSURE; EFFICACY; CANCER;
D O I
10.5489/cuaj.1349
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Introduction: With the increasing number of radical prostatectomies (RP) performed, male stress urinary incontinence (SUI) has become common. The artificial urinary sphincter (AUS) is the gold standard to treat SUI post-RP, but new devices have recently been developed. We review the recent studies on the treatment of SUI post-RP; we also describe the surgical techniques, mechanisms of action and results of these new procedures. Methods: We conducted a literature review search in the PubMed/Medline and Embase databases. Our search was restricted to recent articles. We included studies even if the urinary incontinence was due to sphincter deficiency after RP in non-neurologic patients. Results: We found 8 cohort studies for the surgical procedure: 3 studies concerning slings, 1 involving balloons adjustable implant, and 4 involving new devices. The only randomized controlled trial (RCT) was a pharmacologic clinical trial comparing duloxetine to placebo. The social continence rates were analyzed for 6 studies and were up to 66%. Conclusion: New minimally invasive surgical procedures have emerged as the main alternative to AUS, with social continence rates up to 60% despite just 1 RCT studying the pharmacologic approach. There is an urgent need for well-designed clinical trials to clarify the role of new surgical alternatives in the management of SUI post-RP. New technologies should continue to be evaluated and compared with the AUS, which remains the gold standard.
引用
收藏
页码:202 / 212
页数:11
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