Why Does Australia Appear to Have the Highest Rates of Food Allergy?

被引:20
作者
Allen, Katrina J. [1 ,2 ,3 ,4 ,5 ]
Koplin, Jennifer J. [1 ,4 ]
机构
[1] Royal Childrens Hosp, Ctr Food & Allergy Res, Murdoch Childrens Res Inst, Melbourne, Vic 3052, Australia
[2] Royal Childrens Hosp, Dept Allergy & Clin Immunol, Melbourne, Vic 3052, Australia
[3] Royal Childrens Hosp, Dept Gastroenterol & Clin Nutr, Melbourne, Vic 3052, Australia
[4] Univ Melbourne, Royal Childrens Hosp, Dept Paediat, Melbourne, Vic 3052, Australia
[5] Univ Manchester, Inst Inflammat & Repair, Manchester, Lancs, England
关键词
Peanut allergy; Prevalence; Hygiene hypothesis; Microbial exposure; Migration; Food allergy; Vitamin D; OF-FUNCTION MUTATIONS; PEANUT ALLERGY; RISK-FACTORS; VITAMIN-D; ATOPIC-DERMATITIS; MICROBIAL EXPOSURE; REGIONAL-VARIATION; EGG ALLERGY; INFANTS; PREVALENCE;
D O I
10.1016/j.pcl.2015.07.005
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Australia has reported the highest rates of food allergy, using the gold standard, oral food challenge. This phenomenon, which appears linked to the "modern lifestyle" and has coincided with the explosion of the new diseases of affluence in the 21st century, dubbed "affluenza," has spurred a multitude of theories and academic investigations. This review focuses on potentially modifiable lifestyle factors for the prevention of food allergy and presents the first data to emerge in the Australian context that centers around the dual allergen exposure hypothesis, the vitamin D hypothesis, and the hygiene hypothesis.
引用
收藏
页码:1441 / +
页数:12
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