Rapid Advances of Versatile MXenes for Electrochemical Enzyme-Based Biosensors, Immunosensors, and Nucleic Acid-Based Biosensors

被引：14
作者：
Yao, Bo [1 ,2 ]
Yao, Jiantao [1 ,2 ]
Fan, Zhenqiang [3 ]
Zhao, Jianfeng [1 ,2 ]
Zhang, Kai [3 ]
Huang, Wei [1 ,2 ,4 ,5 ]
机构：
[1] Nanjing Tech Univ NanjingTech, Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM, Key Lab Flexible Elect KLOFE, 30 South Puzhu Rd, Nanjing 211816, Peoples R China
[2] Nanjing Tech Univ NanjingTech, Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM, Inst Adv Mat IAM, 30 South Puzhu Rd, Nanjing 211816, Peoples R China
[3] Jiangsu Inst Nucl Med, NHC Key Lab Jiangsu Key Lab Mol Nucl Med, Wuxi 214063, Jiangsu, Peoples R China
[4] Northwestern Polytech Univ, Shaanxi Inst Flexible Elect SIFE, 127 West Youyi Rd, Xian 710072, Shaanxi, Peoples R China
[5] Nanjing Univ Posts & Telecommun, Inst Adv Mat IAM, Key Lab Organ Elect & Informat Displays, 9 Wenyuan Rd, Nanjing 210023, Peoples R China
来源：
CHEMELECTROCHEM | 2022年 / 9卷 / 11期
关键词：
analytical chemistry; electrochemical biosensor; enzyme-based biosensor; immunosensor; nucleic acid-based biosensor; 2-DIMENSIONAL MATERIALS; TI3C2TX MXENE; MAX-PHASE; BIOMEDICAL APPLICATIONS; CANCER-DIAGNOSIS; LABEL-FREE; GRAPHENE; EXFOLIATION; APTASENSOR; COMPOSITE;
D O I：
10.1002/celc.202200103
中图分类号：
O646 [电化学、电解、磁化学];
学科分类号：
081704 ;
摘要：
Electrochemical biosensors have played an important role in clinical diagnostics, drug analysis, environmental monitoring, food safety, and other fields. Versatile two-dimensional (2D) MXenes-based nanomaterials, born with intrinsic peculiarities including high electrical conductivity, low toxicity, large specific surface area, and good biocompatibility, provide sufficient potential candidates for the construction of universal or specific electrochemical biosensors. In this review, we summarized the latest advances in 2D MXenes nanomaterials for constructing electrochemical enzyme-based biosensors, immunosensors, and nucleic acid-based biosensors in 2021, and then discussed the pertinent roles of corresponding 2D MXenes and carried out a comparison of the difference in the detection limit and detection range. Finally, challenges and future prospects of 2D MXenes-based electrochemical biosensors are proposed and discussed.
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页数：11
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