The Role of Brachytherapy in the Treatment of Breast Cancer

被引:15
作者
Kauer-Dorner, Daniela [1 ]
Berger, Daniel [1 ]
机构
[1] Med Univ Vienna, Dept Radiotherapy, Wahringer Gurtel 18-20, A-1090 Vienna, Austria
关键词
Breast cancer; Brachytherapy; Partial breast irradiation; Boost therapy; DOSE-RATE BRACHYTHERAPY; INTERSTITIAL MULTICATHETER BRACHYTHERAPY; 10-YEAR FOLLOW-UP; PHASE-II TRIAL; CONSERVING SURGERY; CONSERVATIVE TREATMENT; IRRADIATION APBI; IRIDIUM IMPLANT; LUMPECTOMY SITE; BOOST TECHNIQUE;
D O I
10.1159/000489638
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Radiotherapy plays an important part in the management of breast cancer. Especially after breast-conserving surgery, external whole breast irradiation, occasionally with an additional local boost, is an integral part of breast conservation. Besides external radiation techniques, brachytherapy (BT) has long been among the treatment options, especially with regard to local boost application. With the emerging implementation of accelerated partial breast irradiation (APBI), BT in general and interstitial multi-catheter BT in particular, are gaining an increasing role in the management of a selected group of early breast cancer patients. APBI is an approach to reduce the irradiated area to the former tumor bed rather than treating the whole breast tissue in patients with a low baseline local recurrence risk. After a variety of phase I-III clinical studies, it is clearly evident that APBI will play a role in the treatment of this selected patient group. In this review, we focus on the clinical development and different available techniques of breast BT and provide a preview of prospects for its use. (C) 2018 S. Karger GmbH, Freiburg
引用
收藏
页码:157 / 161
页数:5
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