Palladium-Catalyzed Direct Arylation of Electron-Deficient Polyfluoroarenes with Arylboronic Acids

被引：117
|
作者：
Wei, Ye [1 ]
Kan, Jian [1 ]
Wang, Min [1 ]
Su, Weiping [1 ]
Hong, Maochun [1 ]
机构：
[1] Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Fuzhou 350002, Fujian, Peoples R China
来源：
ORGANIC LETTERS | 2009年 / 11卷 / 15期
关键词：
H BOND FUNCTIONALIZATION; CROSS-COUPLING REACTIONS; AROMATIC KETONES; ROOM-TEMPERATURE; N-OXIDES; INDOLES; (HETERO)ARENES; ALKENYLATION; OLEFINATION; ACTIVATION;
D O I：
10.1021/ol901200g
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The palladium-catalyzed direct arylation of electron-deficient arenes that contain two or more fluorine groups with arylboronic acids was realized. The key to achieving a broad substrate scope with respect to both polyfluorobenzenes and arylboronic acids is the choice of bases depending on acidities of polyfluorobenzenes.
引用
收藏
页码：3346 / 3349
页数：4
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