Nurse-like cells mediate ibrutinib resistance in chronic lymphocytic leukemia patients

被引：39
作者：
Boissard, F. [1 ,2 ]
Fournie, J-J [1 ,2 ]
Quillet-Mary, A. [1 ,2 ]
Ysebaert, L. [1 ,2 ,3 ]
Poupot, M. [1 ,2 ]
机构：
[1] Univ Toulouse 3, Ctr Rech Cancerol Toulouse, ERL CNRS 5294, INSERM UMR1037, F-31062 Toulouse, France
[2] Programme Hosp Univ Cancerol CAPTOR, Inst Carnot Lymphome CALYM, Lab Excellence TOUCAN, Pierre Benite, France
[3] CHU Toulouse, Inst Univ Canc Toulouse Oncopole, Toulouse, France
来源：
BLOOD CANCER JOURNAL | 2015年 / 5卷
关键词：
MARROW STROMAL CELLS; B-CELLS; PROLIFERATION; APOPTOSIS; CLL; BTK;
D O I：
10.1038/bcj.2015.74
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页码：e355 / e355
页数：4
相关论文
共 13 条
[1]  
Burger JA, 2000, BLOOD, V96, P2655
[2]   Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells [J].
Burger, JA ;
Burger, M ;
Kipps, TJ .
BLOOD, 1999, 94 (11) :3658-3667
[3]   B cell receptor signaling in chronic lymphocytic leukemia [J].
Burger, Jan A. ;
Chiorazzi, Nicholas .
TRENDS IN IMMUNOLOGY, 2013, 34 (12) :592-601
[4]   Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia [J].
Byrd, John C. ;
Furman, Richard R. ;
Coutre, Steven E. ;
Flinn, Ian W. ;
Burger, Jan A. ;
Blum, Kristie A. ;
Grant, Barbara ;
Sharman, Jeff P. ;
Coleman, Morton ;
Wierda, William G. ;
Jones, Jeffrey A. ;
Zhao, Weiqiang ;
Heerema, Nyla A. ;
Johnson, Amy J. ;
Sukbuntherng, Juthamas ;
Chang, Betty Y. ;
Clow, Fong ;
Hedrick, Eric ;
Buggy, Joseph J. ;
James, Danelle F. ;
O'Brien, Susan .
NEW ENGLAND JOURNAL OF MEDICINE, 2013, 369 (01) :32-42
[5]  
CALIGARISCAPPIO F, 1993, BLOOD CELLS, V19, P601
[6]   BTK inhibition targets in vivo CLL proliferation through its effects on B-cell receptor signaling activity [J].
Cheng, S. ;
Ma, J. ;
Guo, A. ;
Lu, P. ;
Leonard, J. P. ;
Coleman, M. ;
Liu, M. ;
Buggy, J. J. ;
Furman, R. R. ;
Wang, Y. L. .
LEUKEMIA, 2014, 28 (03) :649-657
[7]   An interaction between hepatocyte growth factor and its receptor (c-MET) prolongs the survival of chronic lymphocytic leukemic cells through STAT3 phosphorylation: a potential role of mesenchymal cells in the disease [J].
Giannoni, Paolo ;
Scaglione, Silvia ;
Quarto, Rodolfo ;
Narcisi, Roberto ;
Parodi, Manuela ;
Balleari, Enrico ;
Barbieri, Federica ;
Pattarozzi, Alessandra ;
Florio, Tullio ;
Ferrini, Silvano ;
Corte, Giorgio ;
de Totero, Daniela .
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2011, 96 (07) :1015-1023
[8]   Ibrutinib inhibits BCR and NF-κB signaling and reduces tumor proliferation in tissue-resident cells of patients with CLL [J].
Herman, Sarah E. M. ;
Mustafa, Rashida Z. ;
Gyamfi, Jennifer A. ;
Pittaluga, Stefania ;
Chang, Stella ;
Chang, Betty ;
Farooqui, Mohammed ;
Wiestner, Adrian .
BLOOD, 2014, 123 (21) :3286-3295
[9]   Chronic lymphocytic leukemic B cells but not normal B cells are rescued from apoptosis by contact with normal bone marrow stromal cells [J].
Lagneaux, L ;
Delforge, A ;
Bron, D ;
De Bruyn, C ;
Stryckmans, P .
BLOOD, 1998, 91 (07) :2387-2396
[10]   Ibrutinib in Relapsed Chronic Lymphocytic Leukemia [J].
Neffendorf, James E. ;
Gout, Irina ;
Hildebrand, G. Darius .
NEW ENGLAND JOURNAL OF MEDICINE, 2013, 369 (13) :1277-1277
12