Immunotherapy for non-small cell lung cancer: from clinical trials to real-world practice

被引:20
作者
Rashdan, Sawsan [1 ,2 ]
Gerber, David E. [1 ,2 ,3 ]
机构
[1] Univ Texas Southwestern Med Ctr Dallas, Div Hematol Oncol, Dept Internal Med, 5323 Harry Hines Blvd,Mail Code 8852, Dallas, TX 75390 USA
[2] Univ Texas Southwestern Med Ctr Dallas, Harold C Simmons Comprehens Canc Ctr, Dallas, TX 75390 USA
[3] Univ Texas Southwestern Med Ctr Dallas, Dept Clin Sci, Dallas, TX 75390 USA
关键词
PHASE-II TRIAL; POOR PERFORMANCE STATUS; OPEN-LABEL; NIVOLUMAB; DOCETAXEL; ATEZOLIZUMAB; PEMBROLIZUMAB; PARTICIPATION; MULTICENTER; CARBOPLATIN;
D O I
10.21037/tlcr.2018.09.15
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页码:202 / 207
页数:6
相关论文
共 36 条
[1]  
American Autoimmune Related Diseases Association Inc, AUT DIS STAT
[2]  
Antonia SJ, 2018, NEW ENGL J MED, V378, P869, DOI 10.1056/NEJMc1716426
[3]   Real world data of nivolumab for previously treated non-small cell lung cancer patients: a Galician lung cancer group clinical experience [J].
Areses Manrique, Ma Carmen ;
Mosquera Martinez, Joaquin ;
Garcia Gonzalez, Jorge ;
Afonso Afonso, Francisco Javier ;
Lazaro Quintela, Martin ;
Fernandez Nunez, Natalia ;
Azpitarte Raposeiras, Cristina ;
Amenedo Gancedo, Margarita ;
Santome Couto, Lucia ;
Garcia Campelo, Ma Rosario ;
Munoz Iglesias, Jose ;
Cortegoso Mosquera, Alexandra ;
Vilchez Simo, Rocio ;
Casal Rubio, Joaquin ;
Campos Balea, Begona ;
Carou Frieiro, Iria ;
Alonso-Jaudenes Curbera, Guillermo ;
Anido Herranz, Urbano ;
Garcia Mata, Jesus ;
Firvida Perez, Jose Luis .
TRANSLATIONAL LUNG CANCER RESEARCH, 2018, 7 (03) :404-415
[4]   Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer [J].
Borghaei, H. ;
Paz-Ares, L. ;
Horn, L. ;
Spigel, D. R. ;
Steins, M. ;
Ready, N. E. ;
Chow, L. Q. ;
Vokes, E. E. ;
Felip, E. ;
Holgado, E. ;
Barlesi, F. ;
Kohlhaeufl, M. ;
Arrieta, O. ;
Burgio, M. A. ;
Fayette, J. ;
Lena, H. ;
Poddubskaya, E. ;
Gerber, D. E. ;
Gettinger, S. N. ;
Rudin, C. M. ;
Rizvi, N. ;
Crino, L. ;
Blumenschein, G. R. ;
Antonia, S. J. ;
Dorange, C. ;
Harbison, C. T. ;
Finckenstein, F. Graf ;
Brahmer, J. R. .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 373 (17) :1627-1639
[5]   Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer [J].
Brahmer, Julie ;
Reckamp, Karen L. ;
Baas, Paul ;
Crino, Lucio ;
Eberhardt, Wilfried E. E. ;
Poddubskaya, Elena ;
Antonia, Scott ;
Pluzanski, Adam ;
Vokes, Everett E. ;
Holgado, Esther ;
Waterhouse, David ;
Ready, Neal ;
Gainor, Justin ;
Aren Frontera, Osvaldo ;
Havel, Libor ;
Steins, Martin ;
Garassino, Marina C. ;
Aerts, Joachim G. ;
Domine, Manuel ;
Paz-Ares, Luis ;
Reck, Martin ;
Baudelet, Christine ;
Harbison, Christopher T. ;
Lestini, Brian ;
Spigel, David R. .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 373 (02) :123-135
[6]   Intracranial response to nivolumab in NSCLC patients with untreated or progressing CNS metastases [J].
Dudnik, Elizabeth ;
Yust-Katz, Shlomit ;
Nechushtan, Hovav ;
Goldstein, Daniel A. ;
Zer, Alona ;
Flex, Dov ;
Siegal, Tali ;
Peled, Nir .
LUNG CANCER, 2016, 98 :114-117
[7]   Generalizability of cancer clinical trial results [J].
Elting, LS ;
Cooksley, C ;
Bekele, BN ;
Frumovitz, M ;
Avritscher, EBC ;
Sun, C ;
Bodurka, DC .
CANCER, 2006, 106 (11) :2452-2458
[8]   Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial [J].
Fehrenbacher, Louis ;
Spira, Alexander ;
Ballinger, Marcus ;
Kowanetz, Marcin ;
Vansteenkiste, Johan ;
Mazieres, Julien ;
Park, Keunchil ;
Smith, David ;
Artal-Cortes, Angel ;
Lewanski, Conrad ;
Braiteh, Fadi ;
Waterkamp, Daniel ;
He, Pei ;
Zou, Wei ;
Chen, Daniel S. ;
Yi, Jing ;
Sandler, Alan ;
Rittmeyer, Achim .
LANCET, 2016, 387 (10030) :1837-1846
[9]  
Franks AL, 2012, ANTICANCER RES, V32, P1119
[10]   Pembrolizumab plus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer [J].
Gandhi, L. ;
Rodriguez-Abreu, D. ;
Gadgeel, S. ;
Esteban, E. ;
Felip, E. ;
De Angelis, F. ;
Domine, M. ;
Clingan, P. ;
Hochmair, M. J. ;
Powell, S. F. ;
Cheng, S. Y. -S. ;
Bischoff, H. G. ;
Peled, N. ;
Grossi, F. ;
Jennens, R. R. ;
Reck, M. ;
Hui, R. ;
Garon, E. B. ;
Boyer, M. ;
Rubio-Viqueira, B. ;
Novello, S. ;
Kurata, T. ;
Gray, J. E. ;
Vida, J. ;
Wei, Z. ;
Yang, J. ;
Raftopoulos, H. ;
Pietanza, M. C. ;
Garassino, M. C. .
NEW ENGLAND JOURNAL OF MEDICINE, 2018, 378 (22) :2078-2092