Emergence of Two Distinct SARS-CoV-2 Gamma Variants and the Rapid Spread of P.1-like-II SARS-CoV-2 during the Second Wave of COVID-19 in Santa Catarina, Southern Brazil

被引：10

作者：

Padilha, Dayane Azevedo ^{[1
]}

Benetti Filho, Vilmar ^{[1
]}

Moreira, Renato Simoes ^{[2
]}

Teixeira Soratto, Tatiany Aparecida ^{[1
]}

Maia, Guilherme Augusto ^{[1
]}

Christoff, Ana Paula ^{[3
]}

Barazzetti, Fernando Hartmann ^{[1
]}

Schorner, Marcos Andre ^{[1
]}

Ferrari, Fernanda Luiza ^{[1
]}

Martins, Carolina Leite ^{[1
]}

Kawagoe, Eric Kazuo ^{[1
]}

Wachter, Julia Kinetz ^{[1
]}

Sachet, Paula ^{[4
]}

Baptistella, Antuani Rafael ^{[5
]}

Schlindwein, Aline Daiane ^{[6
]}

Coelho, Bruna Kellet ^{[7
]}

Fernandes, Sandra Bianchini ^{[7
]}

Rovaris, Darcita Buerger ^{[7
]}

Debiasi dos Anjos, Marlei Pickler ^{[7
]}

Melo, Fernanda Rosene ^{[8
]}

Bittencourt, Bianca ^{[8
]}

Cunha, Sthefani ^{[9
]}

Meneghetti, Karine Lena ^{[9
]}

Wendt, Nestor ^{[1
]}

Madaloz, Tamela Zamboni ^{[1
]}

Duarte Rodrigues, Marcus Vinicius ^{[1
]}

Marques Souza, Doris Sobral ^{[1
]}

de Moraes, Milene Hoehr ^{[3
]}

Baptista, Rodrigo de Paula ^{[10
]}

Toledo-Silva, Guilherme ^{[1
]}

Razzera, Guilherme ^{[1
]}

Grisard, Edmundo Carlos ^{[1
]}

Stoco, Patricia Hermes ^{[1
]}

Valter de Oliveira, Luiz Felipe ^{[3
]}

Bazzo, Maria Luiza ^{[1
]}

Fongaro, Gislaine ^{[1
]}

Wagner, Glauber ^{[1
]}

机构：

[1] Univ Fed Santa Catarina, BR-88040900 Florianopolis, SC, Brazil

[2] Inst Fed Santa Catarina, BR-88506400 Lages, SC, Brazil

[3] Biome Hub Pesquisa & Desenvolvimento, BR-88054700 Florianopolis, SC, Brazil

[4] Univ Sao Paulo, BR-05508220 Sao Paulo, Brazil

[5] Univ Oeste Santa Catarina, BR-89600000 Joacaba, Brazil

[6] Secretaria Estado Saude Sao Paulo, BR-88015130 Florianopolis, SC, Brazil

[7] Lab Cent Estado Saude Santa Catarina, BR-88010001 Florianopolis, SC, Brazil

[8] Diretoria Vigilancia Epidemiol Santa Catarina, BR-88015130 Florianopolis, SC, Brazil

[9] Serv Nacl Aprendizagem Ind, BR-70040903 Chapeco, SC, Brazil

[10] Univ Georgia, Athens, GA 30602 USA

来源：

VIRUSES-BASEL | 2022年 / 14卷 / 04期

关键词：

SARS-CoV-2; surveillance; genome; P; 1; variant; MUTATIONS; ALIGNMENT;

D O I：

10.3390/v14040695

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The western mesoregion of the state of Santa Catarina (SC), Southern Brazil, was heavily affected as a whole by the COVID-19 pandemic in early 2021. This study aimed to evaluate the dynamics of the SARS-CoV-2 virus spreading patterns in the SC state from March 2020 to April 2021 using genomic surveillance. During this period, there were 23 distinct variants, including Beta and Gamma, among which the Gamma and related lineages were predominant in the second pandemic wave within SC. A regionalization of P.1-like-II in the Western SC region was observed, concomitant to the increase in cases, mortality, and the case fatality rate (CFR) index. This is the first evidence of the regionalization of the SARS-CoV-2 transmission in SC and it highlights the importance of tracking the variants, dispersion, and impact of SARS-CoV-2 on the public health systems.

引用

页数：16

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