A Novel Group of Transcriptional Repressors in Arabidopsis

被引：205

作者：

Ikeda, Miho ^{[1
]}

Ohme-Takagi, Masaru ^{[1
]}

机构：

[1] Natl Inst Adv Ind Sci & Technol, Res Inst Genome Based Biofactory, Tsukuba, Ibaraki 3058562, Japan

来源：

PLANT AND CELL PHYSIOLOGY | 2009年 / 50卷 / 05期

关键词：

EAR motif; Repressor; Transcription factor; B3; domain; Hsf; RAV; DOMAIN; SUPERMAN; TRANSFORMATION; EXPRESSION; REGULATOR; EFFICIENT; THALIANA; PROTEIN; GENES; MOTIF;

D O I：

10.1093/pcp/pcp048

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

We showed previously that the ERF-associated amphiphilic repression (EAR) motif is a plant-specific repression domain that contains the conserved amino acid sequence LXLXL. In this report, we describe the identification of a novel repression domain, L/VR/KLFGVXM/V/L, which is different from known EAR motifs, in B3 DNA-binding domain transcription factors in Arabidopsis. Database analysis revealed that 29 Arabidopsis transcription factors, which included members of the RAV, ARF, Hsf and MYB families, contain the R/KLFGV conserved motif found in the novel repression domain. We demonstrated that factors that contain the R/KLFGV motif, namely, RAV1, RAV2, HsfB1 and HsfB2b, exhibited the repressive activity.

引用

页码：970 / 975

页数：6

共 17 条

[1] Endogenous and synthetic microRNAs stimulate simultaneous, efficient, and localized regulation of multiple targets in diverse species [J].