Atrial septal defect in adulthood: a new paradigm for congenital heart disease

被引：74

作者：

Brida, Margarita ^{[1
,2
,3
,4
,5
,6
]}

Chessa, Massimo ^{[7
,8
]}

Celermajer, David ^{[9
]}

Li, Wei ^{[1
,2
,3
,4
]}

Geva, Tal ^{[10
,11
]}

Khairy, Paul ^{[12
]}

Griselli, Massimo ^{[13
]}

Baumgartner, Helmut ^{[14
]}

Gatzoulis, Michael A. ^{[1
,2
,3
,4
]}

机构：

[1] Imperial Coll, Natl Heart & Lung Inst, Royal Brompton Hosp, Adult Congenital Heart Ctr, Sydney St, London SW3 6NP, England

[2] Imperial Coll, Natl Heart & Lung Inst, Royal Brompton Hosp, Natl Ctr Pulm Hypertens, Sydney St, London SW3 6NP, England

[3] Imperial Coll, Natl Heart & Lung Inst, Harefield Hosp, Adult Congenital Heart Ctr, Sydney St, London SW3 6NP, England

[4] Imperial Coll, Natl Heart & Lung Inst, Harefield Hosp, Natl Ctr Pulm Hypertens, Sydney St, London SW3 6NP, England

[5] Univ Hosp Ctr Zagreb, Dept Cardiovasc Med, Div Adult Congenital Heart Dis, Kispaticeva Ul 12, Zagreb 10000, Croatia

[6] Univ Rijeka, Med Fac, Dept Med Rehabil, Ul Brace Branchetta 20-1, Rijeka 51000, Croatia

[7] IRCCS Policlin San Donato, Pediat & Adult Congenital Heart Ctr, ACHD Unit, Piazza Edmondo Malan 2, I-20097 Milan, Italy

[8] UniSR Vita Salute San Raffaele Univ, Via Olgettina 58, I-20132 Milan, Italy

[9] Univ Sydney, Heart Res Inst, Camperdown, NSW 2050, Australia

[10] Harvard Med Sch, Boston Childrens Hosp, Dept Cardiol, 300 Longwood Ave, Boston, MA 02115 USA

[11] Harvard Med Sch, Boston Childrens Hosp, Dept Pediat, 300 Longwood Ave, Boston, MA 02115 USA

[12] Univ Montreal, Montreal Heart Inst, Dept Med, 5000 Rue Belanger, Montreal, PQ H1T 1C8, Canada

[13] Univ Minnesota, Mason Childrens Hosp, Div Pediat Cardiovasc Surg, 2450 Riverside Ave, Minneapolis, MN 55454 USA

[14] Univ Hosp Muenster, Dept Cardiol Adult Congenital & Valvular Heart Di, Albert Schweitzer Campus 1, D-48149 Munster, Germany

来源：

EUROPEAN HEART JOURNAL | 2022年 / 43卷 / 28期

关键词：

Atrial septal defect; Sinus venosus defect; Device closure; Atrial septal defect surgery; Advanced imaging; Pulmonary arterial hypertension; PULMONARY ARTERIAL-HYPERTENSION; PATENT FORAMEN OVALE; SUPERIOR VENA-CAVA; TRANSCATHETER CLOSURE; SURGICAL CLOSURE; INTRACARDIAC ECHOCARDIOGRAPHY; PERCUTANEOUS CLOSURE; EISENMENGER-SYNDROME; NATURAL-HISTORY; FOLLOW-UP;

D O I：

10.1093/eurheartj/ehab646

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Atrial septal defects (ASDs) represent the most common congenital heart defect diagnosed in adulthood. Although considered a simple defect, challenges in optimal diagnostic and treatment options still exist due to great heterogeneity in terms of anatomy and time-related complications primarily arrhythmias, thromboembolism, right heart failure and, in a subset of patients, pulmonary arterial hypertension (PAH). Atrial septal defects call for tertiary expertise where all options may be considered, namely catheter vs. surgical closure, consideration of pre-closure ablation for patients with atrial tachycardia and suitability for closure or/and targeted therapy for patients with PAH. This review serves to update the clinician on the latest evidence, the nuances of optimal diagnostics, treatment options, and long-term follow-up care for patients with an ASD.

引用

页码：2660 / +

页数：14

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