Synthesis of 2-Alkynyl 1,3,4-Oxadiazoles by Palladium-Catalyzed Cross-Coupling Reaction

被引：7

作者：

Salvanna, N. ^{[1
]}

Das, Biswanath ^{[1
]}

机构：

[1] Indian Inst Chem Technol, CSIR, Nat Prod Chem Div, Hyderabad 500007, Andhra Pradesh, India

来源：

SYNLETT | 2014年 / 25卷 / 14期

关键词：

1,3,4-oxadiazole; Sonogashira coupling; palladium-catalyzed reaction; copper(I) iodide; alkynylation; C-H ACTIVATION; SONOGASHIRA REACTIONS; TERMINAL ALKYNES; ARYL CHLORIDES; COPPER; BROMIDES; DERIVATIVES; SYSTEMS; POTENT; AGENTS;

D O I：

10.1055/s-0034-1378361

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several 2-alkynyl 1,3,4-oxadiazoles have been synthesized efficiently by employing palladium-catalyzed cross-coupling under Sonogashira reaction conditions. This reaction has been applied for the first time for the preparation of oxadiazole derivatives. The products were formed in high yields and no side products were detected.

引用

页码：2033 / 2035

页数：3

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