Synthesis of new ethyl 3-amino-4-arylfuran-2-carboxylates

被引：0
|
作者：
Lisowski, V [1 ]
Vu, DN [1 ]
Feng, X [1 ]
Rault, S [1 ]
机构：
[1] UFR Sci Pharmaceut, Ctr Etudes & Rech Med Normandie, F-14032 Caen, France
来源：
SYNTHESIS-STUTTGART | 2002年 / 06期
关键词：
furans; amino esters; ring closure;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient method for the preparation of new ethyl 3-amino-4-arylfuran-2-carboxylates is described. The synthesis proceeds via the corresponding hydroxyacrylonitrile sodium salt and an intermediate malonate vinyl ether. The last step of ring closure afforded the ethyl 3-amino-4-arylfuran-2-carboxylates in 15% to 40% yields.
引用
收藏
页码：753 / 756
页数：4
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