Targeted Inhibition of Vav1 Activity Does Not Favour Development of Colitis-Associated Colon Cancer

被引:0
作者
Zenker, Stefanie [1 ]
Neurath, Markus F. [1 ]
Atreya, Imke [1 ]
机构
[1] Univ Erlangen Nurnberg, Med Clin 1, D-91054 Erlangen, Germany
关键词
INFLAMMATORY-BOWEL-DISEASE; AZATHIOPRINE; RISK;
D O I
10.1097/MIB.0b013e31827eeabe
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:E72 / E73
页数:3
相关论文
共 8 条
  • [1] Risk of Cancer in Inflammatory Bowel Disease Treated With Azathioprine: A UK Population-Based Case-Control Study
    Armstrong, Richard G.
    West, Joe
    Card, Timothy R.
    [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2010, 105 (07) : 1604 - 1609
  • [2] Beaugerie L, 2012, GASTROENTEROLOGY S1, V142
  • [3] In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy
    Becker, C
    Fantini, MC
    Wirtz, S
    Nikolaev, A
    Kiesslich, R
    Lehr, HA
    Galle, PR
    Neurath, MF
    [J]. GUT, 2005, 54 (07) : 950 - 954
  • [4] Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine
    Kandiel, A
    Fraser, AG
    Korelitz, BI
    Brensinger, C
    Lewis, JD
    [J]. GUT, 2005, 54 (08) : 1121 - 1125
  • [5] Guidelines for the management of inflammatory bowel disease in adults
    Mowat, Craig
    Cole, Andrew
    Windsor, Al
    Ahmad, Tariq
    Arnott, Ian
    Driscoll, Richard
    Mitton, Sally
    Orchard, Tim
    Rutter, Matt
    Younge, Lisa
    Lees, Charlie
    Ho, Gwo-tzer
    Satsangi, Jack
    Bloom, Stuart
    [J]. GUT, 2011, 60 (05) : 571 - 607
  • [6] An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression
    Neufert, Clemens
    Becker, Christoph
    Neurath, Markus F.
    [J]. NATURE PROTOCOLS, 2007, 2 (08) : 1998 - 2004
  • [7] Azathioprine suppresses ezrin-radixin-moesin-dependent T Cell-APC conjugation through inhibition of Vav guanosine exchange activity on Rac protein
    Poppe, D
    Tiede, I
    Fritz, G
    Becker, C
    Bartsch, B
    Wirtz, S
    Strand, D
    Tanaka, S
    Galle, PR
    Bustelo, XR
    Neurath, MF
    [J]. JOURNAL OF IMMUNOLOGY, 2006, 176 (01) : 640 - 651
  • [8] A requirement for the Rho-family GTP exchange factor Vav in positive and negative selection of thymocytes
    Turner, M
    Mee, PJ
    Walters, AE
    Quinn, ME
    Mellor, AL
    Zamoyska, R
    Tybulewicz, VLJ
    [J]. IMMUNITY, 1997, 7 (04) : 451 - 460