Polymeric nanoparticles for optical sensing

被引：99
作者：
Canfarotta, Francesco [1 ]
Whitcombe, Michael J. [1 ]
Piletsky, Sergey A. [1 ]
机构：
[1] Cranfield Univ, Cranfield Hlth, Cranfield MK43 0AL, Beds, England
来源：
BIOTECHNOLOGY ADVANCES | 2013年 / 31卷 / 08期
关键词：
Polymeric nanoparticles; Diagnostic applications; Optical detection; Fluorescence; Polymeric coatings; Multifunctional nanoparticles; Silica; FLUORESCENT SILICA NANOPARTICLES; MOLECULARLY IMPRINTED POLYMERS; IN-VIVO; QUANTUM DOTS; HYDROGEN-PEROXIDE; SURFACE MODIFICATION; CONJUGATED POLYMERS; MAGNETIC-RESONANCE; URINARY-EXCRETION; CLICK CHEMISTRY;
D O I：
10.1016/j.biotechadv.2013.08.010
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Nanotechnology is a powerful tool for use in diagnostic applications. For these purposes a variety of functional nanoparticles containing fluorescent labels, gold and quantum dots at their cores have been produced, with the aim of enhanced sensitivity and multiplexing capabilities. This work will review progress in the application of polymeric nanoparticles in optical diagnostics, both for in vitro and in vivo detection, together with a discussion of their biodistribution and biocompatibility. (C) 2013 Elsevier Inc. All rights reserved.
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页码：1585 / 1599
页数：15
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